Determination of haplotype phase is becoming increasingly important as we enter the era of
large-scale sequencing because many of its applications, such as imputing low-frequency …

Motivation: DnaSP is a software package for a comprehensive analysis of DNA
polymorphism data. Version 5 implements a number of new features and analytical methods …

Conventional approaches to training a supervised image classification aim to fully describe
all of the classes spectrally. To achieve a complete description of each class in feature …

Interest in the assignment and frequency analysis of haplotypes in samples of unrelated
individuals has increased immeasurably as a result of the emphasis placed on haplotype …

Background The frequency of a haplotype comprising one allele at each of two loci can be
expressed as a cubic equation (the'Hill equation'), the solution of which gives that frequency …

The enormous complexity of biological systems at the molecular level must be answered
with powerful computational methods. Computational biology is a young field, but has seen …

Motivation: Haplotype reconstruction based on aligned single nucleotide polymorphism
(SNP) fragments is to infer a pair of haplotypes from localized polymorphism data gathered …

Signal transduction is an important process that transmits signals from the outside of a cell to
the inside to mediate sophisticated biological responses. Effective computational models to …

One of the main topics of research in genomics is determining the relevance of mutations,
described in haplotype data, as causes of some genetic diseases. However, due to …

Mutation in DNA is the principal cause for differences among human beings, and Single
Nucleotide Polymorphisms (SNPs) are the most common mutations. Hence, a fundamental …