Maintaining blood-brain barrier (BBB) integrity is crucial for the homeostasis of the central
nervous system. Structurally comprising the BBB, brain endothelial cells interact with …

Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

Stroke is the leading cause of disability and thesecond leading cause of death worldwide.
With the global population aged 65 and over growing faster than all other age groups, the …

Stroke is the second highest cause of death globally and a leading cause of disability, with
an increasing incidence in developing countries. Ischaemic stroke caused by arterial …

Stroke is the second leading cause of death worldwide and a leading cause of disability.
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …

Inflammation and immune mechanisms are crucially involved in the pathophysiology of the
development, acute damage cascades, and chronic course after ischemic stroke …

Stroke, including acute ischaemic stroke and intracerebral haemorrhage, results in neuronal
cell death and the release of factors such as damage-associated molecular patterns …

Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …

Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …

Intracerebral haemorrhage is inadequately controlled by current treatments, requiring new
solutions to improve the prognosis. Following the primary injury, a proinflammatory cascade …