TFOS Lifestyle: Impact of elective medications and procedures on the ocular surface

JAP Gomes, DT Azar, C Baudouin, E Bitton, W Chen… - The Ocular Surface, 2023 - Elsevier
The word “elective” refers to medications and procedures undertaken by choice or with a
lower grade of prioritization. Patients usually use elective medications or undergo elective …

Morphological and functional changes of corneal nerves and their contribution to peripheral and central sensory abnormalities

A Guerrero-Moreno, C Baudouin… - Frontiers in cellular …, 2020 - frontiersin.org
The cornea is the most densely innervated and sensitive tissue in the body. The cornea is
exclusively innervated by C-and A-delta fibers, including mechano-nociceptors that are …

The two-faced effects of nerves and neuropeptides in corneal diseases

RML Vitar, P Rama, G Ferrari - Progress in Retinal and Eye Research, 2022 - Elsevier
Corneal nerves are instrumental to maintain cornea integrity through regulation of key
physiological functions such as tear secretion, blink reflex, and neuropeptide turnover …

Alterations in corneal nerves in different subtypes of dry eye disease: an in vivo confocal microscopy study

SM Cox, A Kheirkhah, S Aggarwal, F Abedi… - The Ocular Surface, 2021 - Elsevier
Purpose To evaluate corneal subbasal nerve alterations in evaporative and aqueous-
deficient dry eye disease (DED) as compared to controls. Methods In this retrospective …

[HTML][HTML] BCLA CLEAR Presbyopia: Management with corneal techniques

JP Craig, A Barsam, C Chen… - Contact Lens and …, 2024 - Elsevier
Corneal techniques for enhancing near and intermediate vision to correct presbyopia
include surgical and contact lens treatment modalities. Broad approaches used …

Understanding chronic ocular surface pain: an unmet need for targeted drug therapy

A Galor, P Hamrah, S Haque, N Attal, M Labetoulle - The ocular surface, 2022 - Elsevier
Chronic ocular surface pain (COSP) may be defined as a feeling of pain, perceived as
originating from the ocular surface, that persists for> 3 months. COSP is a complex …

Corneal nerve abnormalities in painful dry eye disease patients

A Guerrero-Moreno, H Liang, N Moreau, J Luzu… - Biomedicines, 2021 - mdpi.com
Background: This study aimed to compare the corneal nerve structural abnormalities
detected using in vivo confocal microscopy (IVCM) in patients with neuropathic corneal pain …

Ocular surface changes associated with ophthalmic surgery

L Mikalauskiene, A Grzybowski… - Journal of Clinical …, 2021 - mdpi.com
Dry eye disease causes ocular discomfort and visual disturbances. Older adults are at a
higher risk of developing dry eye disease as well as needing for ophthalmic surgery …

[HTML][HTML] Neuropathic corneal pain: Tear proteomic and neuromediator profiles, imaging features, and clinical manifestations

C Liu, MTY Lin, IXY Lee, JHF Wong, D Lu… - American journal of …, 2024 - Elsevier
PURPOSE To investigate the tear proteomic and neuromediator profiles, in vivo confocal
microscopy (IVCM) imaging features, and clinical manifestations in neuropathic corneal pain …

Ocular pain in ocular graft-versus-host disease patients with neurotrophic keratopathy

S Wang, RB Singh, E Yuksel, A Musayeva, S Sinha… - The Ocular Surface, 2022 - Elsevier
Purpose Neurotrophic keratopathy (NK) is a degenerative disorder of the cornea
characterized by decreased sensory innervation, epitheliopathy, and impaired epithelial …