Genomic and genetic methods allow investigation of how frequently the same genes are
used by different populations during adaptive evolution, yielding insights into the …

Humans are a colourful species of primate, with human skin, hair and eye coloration having
been influenced by a great variety of evolutionary forces throughout prehistory. Functionally …

Abstract Forensic DNA Phenotyping (FDP), ie the prediction of human externally visible traits
from DNA, has become a fast growing subfield within forensic genetics due to the …

We present a DNA library preparation method that has allowed us to reconstruct a high-
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …

Human skin colour is highly heritable and externally visible with relevance in medical,
forensic, and anthropological genetics. Although eye and hair colour can already be …

Genome-wide association studies and comparative genomics have established major loci
and specific polymorphisms affecting human skin, hair and eye color. Environmental …

The primary biological role of human skin pigmentation is as a mediator of penetration of
ultraviolet radiation (UVR) into the deep layers of skin and the cutaneous circulation. Since …

Background Melasma is a localized chronic acquired hypermelanosis, common in adult
women and which has an important impact on their life quality. Its pathology is unknown …

Vertebrate pigmentation patterns are amongst the best characterised model systems for
studying the genetic basis of adaptive evolution. The wealth of available data on the genetic …

Skin pigmentation is one of the most variable phenotypic traits in humans. A non-
synonymous substitution (rs1426654) in the third exon of SLC24A5 accounts for lighter skin …