Oxidative stress and antioxidant metabolism under adverse environmental conditions: a review

P Garcia-Caparros, L De Filippis, A Gul… - The Botanical …, 2021 - Springer
Reactive oxygen species (ROS) originate as a natural byproduct in standard metabolism of
oxygen activities. The principal sites of ROS generation in the cell are apoplast …

Eukaryotic copper-only superoxide dismutases (SODs): A new class of SOD enzymes and SOD-like protein domains

NG Robinett, RL Peterson, VC Culotta - Journal of Biological Chemistry, 2018 - ASBMB
The copper-containing superoxide dismutases (SODs) represent a large family of enzymes
that participate in the metabolism of reactive oxygen species by disproportionating …

[HTML][HTML] Species boundaries in the human pathogen Paracoccidioides

DA Turissini, OM Gomez, MM Teixeira… - Fungal Genetics and …, 2017 - Elsevier
The use of molecular taxonomy for identifying recently diverged species has transformed the
study of speciation in fungi. The pathogenic fungus Paracoccidioides spp has been …

Genome Diversity, Recombination, and Virulence across the Major Lineages of Paracoccidioides

JF Muñoz, RA Farrer, CA Desjardins, JE Gallo… - MSphere, 2016 - Am Soc Microbiol
The Paracoccidioides genus includes two species of thermally dimorphic fungi that cause
paracoccidioidomycosis, a neglected health-threatening human systemic mycosis endemic …

Anti-immune strategies of pathogenic fungi

CM Marcos, HC De Oliveira, WCMA de Melo… - Frontiers in cellular …, 2016 - frontiersin.org
Pathogenic fungi have developed many strategies to evade the host immune system.
Multiple escape mechanisms appear to function together to inhibit attack by the various …

[HTML][HTML] Emerging role of antioxidants in Alzheimer's disease: insight into physiological, pathological mechanisms and management

S Singh, GD Gupta, KR Aran - Pharmaceutical Science Advances, 2024 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss, cognitive decline, impairment in activities of daily living, and loss of …

[HTML][HTML] Superoxide dismutase and neurological disorders

SB Chidambaram, N Anand, SR Varma… - IBRO Neuroscience …, 2024 - Elsevier
Superoxide dismutase (SOD) is a common antioxidant enzyme found majorly in living cells.
The main physiological role of SOD is detoxification and maintain the redox balance, acts as …

Paracoccidioides Spp.: Virulence Factors and Immune‐Evasion Strategies

E Camacho, GA Niño-Vega - Mediators of inflammation, 2017 - Wiley Online Library
Paracoccidioides spp. are dimorphic fungal pathogens responsible for one of the most
relevant systemic mycoses in Latin America, paracoccidioidomycosis (PCM). Their exact …

The Glycosylphosphatidylinositol-Anchored Superoxide Dismutase of Scedosporium apiospermum Protects the Conidia from Oxidative Stress

C Staerck, H Yaakoub, P Vandeputte, J Tabiasco… - Journal of Fungi, 2021 - mdpi.com
Scedosporium species are common fungal pathogens in patients with cystic fibrosis (CF). To
colonize the CF lungs, fungi must cope with the host immune response, especially the …

Chemical warfare at the microorganismal level: a closer look at the superoxide dismutase enzymes of pathogens

SS Schatzman, VC Culotta - ACS infectious diseases, 2018 - ACS Publications
Superoxide anion radical is generated as a natural byproduct of aerobic metabolism but is
also produced as part of the oxidative burst of the innate immune response design to kill …