Immunomodulatory and allergenic properties of antimicrobial peptides

SV Guryanova, TV Ovchinnikova - International journal of molecular …, 2022 - mdpi.com
With the growing problem of the emergence of antibiotic-resistant bacteria, the search for
alternative ways to combat bacterial infections is extremely urgent. While analyzing the effect …

Artificial intelligence‐based data‐driven strategy to accelerate research, development, and clinical trials of COVID vaccine

A Sharma, T Virmani, V Pathak… - BioMed research …, 2022 - Wiley Online Library
The global COVID‐19 (coronavirus disease 2019) pandemic, which was caused by the
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has resulted in a …

[HTML][HTML] Immunoinformatics and molecular modeling approach to design universal multi-epitope vaccine for SARS-CoV-2

MT Khan, MJ Islam, A Parihar, R Islam, TJ Jerin… - Informatics in medicine …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmittable
and pathogenic human coronavirus that caused a pandemic situation of acute respiratory …

Antibody response to SARS-CoV-2 membrane protein in patients of the acute and convalescent phase of COVID-19

P Jörrißen, P Schütz, M Weiand, R Vollenberg… - Frontiers in …, 2021 - frontiersin.org
Understanding the course of the antibody response directed to individual epitopes of SARS-
CoV-2 proteins is crucial for serological assays and establishment of vaccines. Twenty-one …

Current and prospective computational approaches and challenges for developing COVID-19 vaccines

W Hwang, W Lei, NM Katritsis, M MacMahon… - Advanced drug delivery …, 2021 - Elsevier
Abstract SARS-CoV-2, which causes COVID-19, was first identified in humans in late 2019
and is a coronavirus which is zoonotic in origin. As it spread around the world there has …

Designing a multi-epitope vaccine to control porcine epidemic diarrhea virus infection using immunoinformatics approaches

W Hou, H Wu, S Wang, W Wang, B Wang… - Frontiers in …, 2023 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV), a continuously evolving pathogen, causes severe
diarrhea in piglets with high mortality rates. However, current vaccines cannot provide …

[HTML][HTML] In silico design of a promiscuous chimeric multi-epitope vaccine against Mycobacterium tuberculosis

BT Andongma, Y Huang, F Chen, Q Tang… - Computational and …, 2023 - Elsevier
Tuberculosis (TB) is a global health threat, killing approximately 1.5 million people each
year. The eradication of Mycobacterium tuberculosis, the main causative agent of TB, is …

Multi-epitope peptide vaccines targeting dengue virus serotype 2 created via immunoinformatic analysis

RN Morgan, NSM Ismail, MY Alshahrani… - Scientific Reports, 2024 - nature.com
Abstract The Middle East has witnessed a greater spread of infectious Dengue viruses, with
serotype 2 (DENV-2) being the most prevalent form. Through this work, multi-epitope …

Design of a recombinant multivalent epitope vaccine based on SARS-CoV-2 and its variants in immunoinformatics approaches

M Yu, Y Zhu, Y Li, Z Chen, Z Li, J Wang, Z Li… - Frontiers in …, 2022 - frontiersin.org
The development of an effective multivalent vaccine against SARS-CoV-2 variants is an
important means to improve the global public health situation caused by COVID-19. In this …

Development and immunological evaluation of an mRNA-based vaccine targeting Naegleria fowleri for the treatment of primary amoebic meningoencephalitis

M Naveed, U Ali, T Aziz, K Jabeen, MH Arif… - Scientific Reports, 2024 - nature.com
More than 95% of patients fall victim to primary amoebic meningoencephalitis (PAM), a fatal
disease attacking the central nervous system. Naegleria fowleri, a brain-eating …