Robustness of microbiome function

KK Lee, Y Park, S Kuehn - Current Opinion in Systems Biology, 2023 - Elsevier
Microbial communities perform metabolic processes that sustain life on Earth and promote
human health. Microbial consortia sustain these functions in the face of constant structural …

The architecture of theory and data in microbiome design: towards an S-matrix for microbiomes

S Arya, AB George, J O'Dwyer - Current Opinion in Microbiology, 2025 - Elsevier
Designing microbiomes for applications in health, bioengineering, and sustainability is
intrinsically linked to a fundamental theoretical understanding of the rules governing …

Sparse species interactions reproduce abundance correlation patterns in microbial communities

J Camacho-Mateu, A Lampo, M Sireci… - Proceedings of the …, 2024 - National Acad Sciences
During the last decades, macroecology has identified broad-scale patterns of abundances
and diversity of microbial communities and put forward some potential explanations for …

Stochastic models allow improved inference of microbiome interactions from time series data

R Zapién-Campos, F Bansept, A Traulsen - PLoS biology, 2024 - journals.plos.org
How can we figure out how the different microbes interact within microbiomes? To combine
theoretical models and experimental data, we often fit a deterministic model for the mean …

Deconstructing inflammatory memory across tissue setpoints using cell circuit motifs

AC Kwong, J Ordovas-Montanes - Journal of Allergy and Clinical …, 2024 - Elsevier
Tissue ecosystems are cellular communities that maintain setpoints through a network of
intercellular interactions. We position health and chronic inflammatory disease as alternative …

[PDF][PDF] mbDriver: identifying driver microbes in microbial communities based on time-series microbiome data

X Tan, F Xue, C Zhang, T Wang - Briefings in Bioinformatics, 2024 - academic.oup.com
Alterations in human microbial communities are intricately linked to the onset and
progression of diseases. Identifying the key microbes driving these community changes is …

[HTML][HTML] Stability of human gut microbiome: Comparison of ecological modelling and observational approaches

A Revel-Muroz, M Akulinin, P Shilova, A Tyakht… - Computational and …, 2023 - Elsevier
The gut microbiome plays a pivotal role in the human body, and perturbations in its
composition have been linked to various disorders. Stability is an essential property of a …

Assembly archetypes in ecological communities

H Flores-Arguedas… - Journal of the …, 2023 - royalsocietypublishing.org
An instrumental discovery in comparative and developmental biology is the existence of
assembly archetypes that synthesize the vast diversity of organisms' body plans—from legs …

EMBED: Essential MicroBiomE Dynamics, a dimensionality reduction approach for longitudinal microbiome studies

M Shahin, B Ji, PD Dixit - npj Systems Biology and Applications, 2023 - nature.com
Dimensionality reduction offers unique insights into high-dimensional microbiome dynamics
by leveraging collective abundance fluctuations of multiple bacteria driven by similar …

mbtransfer: Microbiome intervention analysis using transfer functions and mirror statistics

K Sankaran, P Jeganathan - PLOS Computational Biology, 2024 - journals.plos.org
Time series studies of microbiome interventions provide valuable data about microbial
ecosystem structure. Unfortunately, existing models of microbial community dynamics have …