Objectives: Dramatic increases in opioid and drug overdose mortality have occurred in the
United States (US) over the past two decades. To address this national public health crisis …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder, which affects 1 in 44
children and may cause severe disabilities. Besides socio-communicational difficulties and …

Aim To test the effect of the duration of medication for opioid use disorder (MOUD) use
during pregnancy on maternal, perinatal and neonatal outcomes. Design Retrospective …

The rates of opioid use disorder during pregnancy have more than quadrupled in the last
decade, resulting in numerous infants suffering exposure to opioids during the perinatal …

Despite the rising prevalence of methadone treatment in pregnant women with opioid use
disorder, the effects of methadone on neurobehavioral development remain unclear. We …

Background: Due to its negative effects on the unborn child and the mother as a consumer,
pregnant women's intake of psychoactive substances has become a public health concern …

OBJECTIVES Evidence on the perinatal health of mother-infant dyads affected by opioids is
limited. Elevated risks of opioid-related harms for people with opioid use disorder (OUD) …

The heightened incidence of opioid use during pregnancy has resulted in unprecedented
rates of neonates prenatally exposed to opioids. Prenatal opioid exposure (POE) results in …

Objective To evaluate the association between opioid prescribing during pregnancy and
new persistent opioid use in the year following delivery. Materials and Methods This …

Physiologically-based pharmacokinetic (PBPK) modeling has emerged as a useful tool to
study pharmacokinetics (PK) in special populations, such as pregnant women, fetuses, and …