Prevalence of familial hypercholesterolemia among the general population and patients with atherosclerotic cardiovascular disease: a systematic review and meta …

P Hu, KI Dharmayat, CAT Stevens, MTA Sharabiani… - Circulation, 2020 - Am Heart Assoc
Background: Contemporary studies suggest that familial hypercholesterolemia (FH) is more
frequent than previously reported and increasingly recognized as affecting individuals of all …

Familial hypercholesterolemia: global burden and approaches

L Tokgozoglu, M Kayikcioglu - Current cardiology reports, 2021 - Springer
Abstract Purpose of Review Familial hypercholesterolemia (FH) is the most common genetic
metabolic disorder characterized by markedly elevated LDL-C levels from birth leading to …

Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study

TR Tromp, ML Hartgers, GK Hovingh, AJ Vallejo-Vaz… - The Lancet, 2022 - thelancet.com
Summary Background Homozygous familial hypercholesterolaemia (HoFH) is a rare
inherited disorder resulting in extremely elevated low-density lipoprotein cholesterol levels …

Reducing the clinical and public health burden of familial hypercholesterolemia: a global call to action

KA Wilemon, J Patel, C Aguilar-Salinas… - JAMA …, 2020 - jamanetwork.com
Importance Familial hypercholesterolemia (FH) is an underdiagnosed and undertreated
genetic disorder that leads to premature morbidity and mortality due to atherosclerotic …

Familial hypercholesterolaemia: evolving knowledge for designing adaptive models of care

GF Watts, SS Gidding, P Mata, J Pang… - Nature Reviews …, 2020 - nature.com
Optimal care for familial hypercholesterolaemia (FH) requires patient-centred management,
multidisciplinary teamwork, involvement of primary care practitioners, patient networks …

Screening in children for familial hypercholesterolaemia: start now

U Groselj, A Wiegman, SS Gidding - European Heart Journal, 2022 - academic.oup.com
Screening in children for familial hypercholesterolaemia: start now Page 1 Screening in children
for familial hypercholesterolaemia: start now Urh Groselj 1 , Albert Wiegman 2 , and Samuel S …

Paediatric familial hypercholesterolaemia screening in Europe: public policy background and recommendations

SS Gidding, A Wiegman, U Groselj… - European journal of …, 2022 - academic.oup.com
Familial hypercholesterolaemia (FH) is under-recognized and under-treated in Europe
leading to significantly higher risk for premature heart disease in those affected. As treatment …

Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

AJ Vallejo-Vaz, CAT Stevens, ARM Lyons… - The Lancet, 2021 - thelancet.com
Summary Background The European Atherosclerosis Society Familial
Hypercholesterolaemia Studies Collaboration (FHSC) global registry provides a platform for …

Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic

M Banach, PE Penson, Z Fras, M Vrablik, D Pella… - Pharmacological …, 2020 - Elsevier
Abstract Individuals with Familial Hypercholesterolaemia (FH) are at very high risk of
cardiovascular disease, which is associated with poor outcomes from coronavirus infections …

Current role of lipoprotein apheresis

G Thompson, KG Parhofer - Current atherosclerosis reports, 2019 - Springer
Abstract Purpose of Review Lipoprotein apheresis is a very efficient but time-consuming and
expensive method of lowering levels of low-density lipoprotein cholesterol, lipoprotein (a)) …