Gastric cancer constitutes one of the most prevalent malignancies in both sexes; it is
currently the fourth major cause of cancer-related deaths worldwide. The pathogenesis of …

Although most H. pylori infectors are asymptomatic, some may develop serious disease,
such as gastric adenocarcinoma, gastric high-grade B cell lymphoma and peptic ulcer …

Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Helicobacter pylori plays an essential role in the development of various gastroduodenal
diseases; however, only a small proportion of people infected with H. pylori develop these …

Peptic ulcer disease had a tremendous effect on morbidity and mortality until the last
decades of the 20th century, when epidemiological trends started to point to an impressive …

Although gastric adenocarcinoma is associated with the presence of Helicobacter pylori in
the stomach, only a small fraction of colonized individuals develop this common malignancy …

Helicobacter pylori is highly adapted for colonization of the human stomach and is present in
about half of the human population. When present, H pylori is usually the numerically …

The discovery of Helicobacter pylori in 1982 was the starting point of a revolution concerning
the concepts and management of gastroduodenal diseases. It is now well accepted that the …

Bacterial protein toxins alter eukaryotic cellular processes and enable bacteria to
successfully colonize their hosts. In recent years, there has been increased recognition that …

▪ Abstract Helicobacter pylori is a gram-negative bacterium that resides under microaerobic
conditions in a neutral microenvironment between the mucus and the superficial epithelium …