Covalent labeling of nucleic acids

N Klöcker, FP Weissenboeck… - Chemical Society Reviews, 2020 - pubs.rsc.org
Labeling of nucleic acids is required for many studies aiming to elucidate their functions and
dynamics in vitro and in cells. Out of the numerous labeling concepts that have been …

Chemical and biochemical perspectives of protein lysine methylation

M Luo - Chemical reviews, 2018 - ACS Publications
Protein lysine methylation is a distinct posttranslational modification that causes minimal
changes in the size and electrostatic status of lysine residues. Lysine methylation plays …

S‐Adenosyl‐Methionine‐Dependent Methyltransferases: Highly Versatile Enzymes in Biocatalysis, Biosynthesis and Other Biotechnological Applications

AW Struck, ML Thompson, LS Wong… - …, 2012 - Wiley Online Library
S‐adenosyl methionine (SAM) is a universal biological cofactor that is found in all branches
of life where it plays a critical role in the transfer of methyl groups to various biomolecules …

SAM/SAH analogs as versatile tools for SAM-dependent methyltransferases

J Zhang, YG Zheng - ACS chemical biology, 2016 - ACS Publications
S-Adenosyl-L-methionine (SAM) is a sulfonium molecule with a structural hybrid of
methionine and adenosine. As the second largest cofactor in the human body, its major …

DNA-multichromophore systems

YN Teo, ET Kool - Chemical reviews, 2012 - ACS Publications
1. INTRODUCTION: GOALS OF MULTICHROMOPHORE STUDIES Multichromophoric
systems have gained intense interest in recent decades. 1 The arraying of chromophores at …

CRISPRi-mediated metabolic engineering of E. coli for O-methylated anthocyanin production

BF Cress, QD Leitz, DC Kim, TD Amore, JY Suzuki… - Microbial cell …, 2017 - Springer
Background Anthocyanins are a class of brightly colored, glycosylated flavonoid pigments
that imbue their flower and fruit host tissues with hues of predominantly red, orange, purple …

Broadening the scope of biocatalytic C–C bond formation

LE Zetzsche, ARH Narayan - Nature Reviews Chemistry, 2020 - nature.com
Enzymes exercise impeccable control over chemoselectivity, site selectivity and
stereoselectivity in reactions they mediate, such that we have witnessed a surge in the …

Recent trends and novel concepts in cofactor-dependent biotransformations

S Kara, JH Schrittwieser, F Hollmann… - Applied microbiology …, 2014 - Springer
Cofactor-dependent enzymes catalyze a broad range of synthetically useful transformations.
However, the cofactor requirement also poses economic and practical challenges for the …

Methylation mediated by an anthocyanin, O-methyltransferase, is involved in purple flower coloration in Paeonia

H Du, J Wu, KX Ji, QY Zeng, MW Bhuiya… - Journal of …, 2015 - academic.oup.com
Anthocyanins are major pigments in plants. Methylation plays a role in the diversity and
stability of anthocyanins. However, the contribution of anthocyanin methylation to flower …

[图书][B] DNA and RNA modification enzymes: structure, mechanism, function and evolution

H Grosjean - 2009 - taylorfrancis.com
This volume is a timely and comprehensive description of the many facets of DNA and RNA
modification-editing processes and to some extent repair mechanisms. Each chapter offers …