Sepsis is a life-threatening condition and a global disease burden. Today, the
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …

The cardiovascular system plays a key role in sepsis, and septic myocardial depression is a
common finding associated with increased morbidity and mortality. Myocardial depression …

Background Post-mortem studies can provide important information for understanding new
diseases and small autopsy case series have already reported different findings in COVID …

Summary Background TargomiRs are minicells (EnGeneIC Dream Vectors) loaded with miR-
16-based mimic microRNA (miRNA) and targeted to EGFR that are designed to counteract …

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. Myocardial dysfunction, often termed sepsis-induced cardiomyopathy …

Myocardial dysfunction is a serious consequence of sepsis and contributes to high mortality.
Currently, the molecular mechanism of myocardial dysfunction induced by sepsis remains …

It is well known that cardiac dysfunction in sepsis is associated with significantly increased
mortality. The pathophysiology of sepsis-induced cardiac dysfunction can be summarized as …

Sepsis is the manifestation of the immune and inflammatory response to infection that may
ultimately result in multi organ failure. Despite the therapeutic strategies that have been …

Background Sepsis is a systemic inflammatory response to a local severe infection that may
lead to multiple organ failure and death. Previous studies have shown that 40–50% of …

The regulation of body fluid balance is a key concern in health and disease and comprises
three concepts. The first concept pertains to the relationship between total body water (TBW) …