The role of interferon-gamma in hematopoietic stem cell development, homeostasis, and disease
DE Morales-Mantilla, KY King - Current stem cell reports, 2018 - Springer
Abstract Purpose of Review Interferon-gamma (IFN-γ) is a pro-inflammatory cytokine that
participates in the regulation of hematopoietic stem cells (HSC) during development and …
participates in the regulation of hematopoietic stem cells (HSC) during development and …
Secretome within the bone marrow microenvironment: A basis for mesenchymal stem cell treatment and role in cancer dormancy
HS Eltoukhy, G Sinha, CA Moore, M Gergues… - Biochimie, 2018 - Elsevier
The secretome produced by cells within the bone marrow is significant to homeostasis. The
bone marrow, a well-studied organ, has multiple niches with distinct roles for supporting …
bone marrow, a well-studied organ, has multiple niches with distinct roles for supporting …
CCN2 (Cellular Communication Network factor 2) in the bone marrow microenvironment, normal and malignant hematopoiesis
RJ Leguit, RAP Raymakers, KM Hebeda… - Journal of cell …, 2021 - Springer
CCN2, formerly termed Connective Tissue Growth Factor, is a protein belonging to the
Cellular Communication Network (CCN)-family of secreted extracellular matrix-associated …
Cellular Communication Network (CCN)-family of secreted extracellular matrix-associated …
CXCL12-abundant reticular (CAR) cells direct megakaryocyte protrusions across the bone marrow sinusoid wall
N Wagner, K Mott, B Upcin, D Stegner, H Schulze… - Cells, 2021 - mdpi.com
Megakaryocytes (MKs) release platelets into the lumen of bone marrow (BM) sinusoids
while remaining to reside within the BM. The morphogenetic events of this complex process …
while remaining to reside within the BM. The morphogenetic events of this complex process …
Investigating cancer cell dormancy and recurrence in the bone marrow niche
J Casson - 2020 - theses.gla.ac.uk
Breast cancer is the most commonly diagnosed form of cancer in women. The spread of
metastatic cancer cells to secondary sites, such as the bone marrow, is the leading cause of …
metastatic cancer cells to secondary sites, such as the bone marrow, is the leading cause of …