Ruthenium-based photoactivated chemotherapy

S Bonnet - Journal of the American Chemical Society, 2023 - ACS Publications
Ruthenium (II) polypyridyl complexes form a vast family of molecules characterized by their
finely tuned photochemical and photophysical properties. Their ability to undergo excited …

Development of Biotechnological Photosensitizers for Photodynamic Therapy: Cancer Research and Treatment—From Benchtop to Clinical Practice

M Aires-Fernandes, R Botelho Costa… - Molecules, 2022 - mdpi.com
Photodynamic therapy (PDT) is a noninvasive therapeutic approach that has been applied
in studies for the treatment of various diseases. In this context, PDT has been suggested as …

A new high-throughput-screening-assay for photoantimicrobials based on EUCAST revealed unknown photoantimicrobials in cortinariaceae

J Fiala, H Schöbel, P Vrabl, D Dietrich… - Frontiers in …, 2021 - frontiersin.org
Antimicrobial resistance is one of the biggest health and subsequent economic threat
humanity faces. Next to massive global awareness campaigns, governments and NGOs …

Does the chemistry of fungal pigments demand the existence of photoactivated defense strategies in basidiomycetes?

B Siewert - Photochemical & Photobiological Sciences, 2021 - Springer
The well-known photosensitizers hypericin, harmane, and emodin are typical pigments of
certain mushroom species—is this a coincidence or an indication towards a photoactivated …

Highlighting the phototherapeutical potential of fungal pigments in various fruiting body extracts with informed feature-based molecular networking

F Hammerle, L Quirós-Guerrero, JL Wolfender… - Microbial Ecology, 2023 - Springer
Fungal pigments are characterized by a diverse set of chemical backbones, some of which
present photosensitizer-like structures. From the genus Cortinarius, for example, several …

[HTML][HTML] The photosensitizer emodin is concentrated in the gills of the fungus Cortinarius rubrophyllus

B Siewert, G Ćurak, F Hammerle, L Huymann… - … of Photochemistry and …, 2022 - Elsevier
The colorful agaricoid fruiting bodies of dermocyboid Cortinarii owe their magnificent hue to
a mixture of anthraquinone (AQ) pigments. Recently, it was discovered that some of these …

Fungal Anthraquinone Photoantimicrobials Challenge the Dogma of Cationic Photosensitizers

F Hammerle, J Fiala, A Höck, L Huymann… - Journal of Natural …, 2023 - ACS Publications
The photoantimicrobial potential of four mushroom species (ie, Cortinarius cinnabarinus, C.
holoxanthus, C. malicorius, and C. sanguineus) was explored by studying the minimal …

Photochemical defense as trait of fungi from Cortinarius subgenus Dermocybe

A Hannecker, L Huymann, F Hammerle… - Photochemical & …, 2023 - Springer
The photobiological activity of ten colorful species belonging to subgenus Dermocybe of the
basidiomycete genus Cortinarius was investigated. Extracts of all species produced singlet …

Feature-Based Molecular Networking—An Exciting Tool to Spot Species of the Genus Cortinarius with Hidden Photosensitizers

F Hammerle, L Quirós-Guerrero, A Rutz, JL Wolfender… - Metabolites, 2021 - mdpi.com
Fungi have developed a wide array of defense strategies to overcome mechanical injuries
and pathogen infections. Recently, photoactivity has been discovered by showing that …

Revised taxon definition in European Cortinarius subgenus Dermocybe based on phylogeny, chemotaxonomy, and morphology

LR Huymann, A Hannecker, T Giovanni… - Mycological …, 2024 - Springer
Abstract Cortinarius (Fr.) Fr. is one of the most species-rich genera in the Agaricales
(Basidiomycota). Cortinarius subgen. Dermocybe (Fr.) Trog includes brightly coloured …