The role of substance P in stress and anxiety responses

K Ebner, N Singewald - Amino acids, 2006 - Springer
Substance P (SP) is one of the most abundant peptides in the central nervous system and
has been implicated in a variety of physiological and pathophysiological processes …

Neurokinin‐1 receptor: functional significance in the immune system in reference to selected infections and inflammation

SD Douglas, SE Leeman - Annals of the New York Academy of …, 2011 - Wiley Online Library
The G protein–coupled receptor (GPCR), neurokinin‐1 receptor (NK1R), and its preferred
ligand, substance P (SP), are reviewed in relationship to the immune system and selected …

Long-term repetitive transcranial magnetic stimulation increases the expression of brain-derived neurotrophic factor and cholecystokinin mRNA, but not neuropeptide …

MB Müller, N Toschi, AE Kresse, A Post… - …, 2000 - Elsevier
Repetitive transcranial magnetic stimulation (rTMS) is increasingly used as a therapeutic
tool in various neurological and psychiatric disorders, and we recently found that it has a …

Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin

C Becker, B Zeau, C Rivat, A Blugeot, M Hamon… - Molecular …, 2008 - nature.com
Cholecystokinin (CCK) involvement in depression-like disorders is poorly documented.
Here, we investigated whether CCKergic neurotransmission is relevant to depressive-like …

Do substance P and the NK1 receptor have a role in depression and anxiety?

S McLean - Current pharmaceutical design, 2005 - ingentaconnect.com
Research on Substance P (SP) has, until recently, focused on its role in pain and
inflammation. However, a report that NK1 receptor antagonists have utility in the treatment of …

Enhanced cortical extracellular levels of cholecystokinin-like material in a model of anticipation of social defeat in the rat

C Becker, MH Thiébot, Y Touitou, M Hamon… - Journal of …, 2001 - Soc Neuroscience
The involvement of cholecystokinin (CCK) in the mechanisms of stress and/or anxiety was
assessed by in vivo microdialysis in rats subjected to a social stress paradigm. During the …

Spatiotemporal selective effects on brain-derived neurotrophic factor andtrkB messenger RNA in rat hippocampus by electroconvulsive shock

N Lindefors, E Brodin, M Metsis - Neuroscience, 1995 - Elsevier
Electroconvulsive therapy is used in the treatment of affective disorders and schizophrenia
and experimental electroconvulsive shock may serve as an animal model for this treatment …

Central changes in nociceptin dynorphin B and Met-enkephalin-Arg-Phe in different models of nociception

A Rosén, T Lundeberg, B Bytner, I Nylander - Brain research, 2000 - Elsevier
The newly identified neuropeptide nociceptin/orphanin FQ (NOC) was measured in different
rat brain areas related to the descending anti-nociceptive pathways and compared to two …

Pentagastrin infusions in patients with panic disorder II. Neuroendocrinology

JL Abelson, RM Nesse, AI Vinik - Biological psychiatry, 1994 - Elsevier
Cholecystokinin (CCK) has well-documented anxiogenic effects in animals and normal
people, and panicogenic effects in patients with panic disorder, but little is known about its …

Cholecystokinin and psychiatric disorders: role in aetiology and potential of receptor antagonists in therapy

J Shlik, E Vasar, J Bradwejn - CNS drugs, 1997 - Springer
Cholecystokinin (CCK) is one of the most abundant neuropeptides in the brain. It is found in
the highest levels in cortical and limbic structures and also in the basal ganglia. Two …