Aging is driven by hallmarks fulfilling the following three premises:(1) their age-associated
manifestation,(2) the acceleration of aging by experimentally accentuating them, and (3) the …

Both aging and cancer are characterized by a series of partially overlapping" hallmarks" that
we subject here to a meta-analysis. Several hallmarks of aging (ie, genomic instability …

Short-chain fatty acids (SCFAs) play a key role in health and disease, as they regulate gut
homeostasis and their deficiency is involved in the pathogenesis of several disorders …

Background Recently, the hallmarks of aging were updated to include dysbiosis, disabled
macroautophagy, and chronic inflammation. In particular, the low-grade chronic …

Alzheimer's disease is a complex neurodegenerative disorder leading to a decline in
cognitive function and mental health. Recent research has positioned the gut microbiota as …

Aging, as a complex process involving multiple cellular and molecular pathways, is known to
be exacerbated by various stresses. Because responses to these stresses, such as oxidative …

Accumulating evidence indicates gut microbiota contributes to aging-related disorders.
However, the exact mechanism underlying gut dysbiosis-related pathophysiological …

The gut microbiome is a modifier of disease risk because it interacts with nutrition,
metabolism, immunity and infection. Aging-related health loss has been correlated with …

Dysbiosis is associated with various diseases. The composition and diversity of gut
microbiota affect host physiology through the production of bioactive metabolites. Short …

There is growing appreciation of key roles of the gut microbiota in maintaining homeostasis
and influencing brain and behaviour at critical windows across the lifespan. Mounting …