The rapid development of microfluidics technology has promoted new innovations in
materials science, particularly by interacting with biological systems, based on precise …

Microfluidics and novel lab-on-a-chip applications have the potential to boost
biotechnological research in ways that are not possible using traditional methods. Although …

Membraneless organelles formed by liquid–liquid phase separation are dynamic structures
that are employed by cells to spatiotemporally regulate their interior. Indeed, complex …

The cellular morphology and sub-cellular spatial structure critically influence the function of
microbial cells. Similarly, the spatial arrangement of genotypes and phenotypes in microbial …

Bioprocesses are scaled up for the production of large product quantities. With larger
fermenter volumes, mixing becomes increasingly inefficient and environmental gradients get …

Highlights•A major challenge for the investigation of microbial consortia is a lack of
analytical tools.•Microfluidic tools are emerging for the analysis of microbial …

Heterogeneity in cell populations is a phenomenon encountered in virtually all biological
systems, in whole tissues and cell cultures and from bacterial to mammalian cells. Moreover …

The ability of bacteria to respond to changes in their environment is critical to their survival,
allowing them to withstand stress, form complex communities, and induce virulence …

While microscopy-based cellular assays, including microfluidics, have significantly
advanced over the last several decades, there has not been concurrent development of …

Industrial biotechnology encompasses a large area of multi-scale and multi-disciplinary
research activities. With the recent megatrend of digitalization sweeping across all …