Isolation and structure elucidation of most of the major cannabinoid constituents—including Δ9-tetrahydrocannabinol (Δ9-THC), which is the principal psychoactive molecule in …
C Kang, B Wang, K Kaliannan, X Wang, H Lang, S Hui… - MBio, 2017 - Am Soc Microbiol
Metabolic endotoxemia originating from dysbiotic gut microbiota has been identified as a primary mediator for triggering the chronic low-grade inflammation (CLGI) responsible for …
P Pacher, G Kunos - The FEBS journal, 2013 - Wiley Online Library
The discovery of the endocannabinoid system, comprising the G‐protein coupled cannabinoid 1 and 2 receptors (CB 1/2), their endogenous lipid ligands or …
RG Pertwee - … Transactions of the Royal Society B …, 2012 - royalsocietypublishing.org
Human tissues express cannabinoid CB1 and CB2 receptors that can be activated by endogenously released 'endocannabinoids' or exogenously administered compounds in a …
The mammalian body has a highly developed immune system which guards against continuous invading protein attacks and aims at preventing, attenuating or repairing the …
The actions of cannabis are mediated by receptors that are part of an endogenous cannabinoid system. The endocannabinoid system (ECS) consists of the naturally occurring …
Cannabis has been used to treat gastrointestinal (GI) conditions that range from enteric infections and inflammatory conditions to disorders of motility, emesis and abdominal pain …
JA Galli, R Andari Sawaya… - Current drug abuse …, 2011 - ingentaconnect.com
Coinciding with the increasing rates of cannabis abuse has been the recognition of a new clinical condition known as Cannabinoid Hyperemesis Syndrome. Cannabinoid …
RG Pertwee - British journal of pharmacology, 2009 - Wiley Online Library
Mandarin translation of abstract Medicines that activate cannabinoid CB1 and CB2 receptor are already in the clinic. These are Cesamet®(nabilone), Marinol®(dronabinol; Δ9 …