[HTML][HTML] Diversity and pathogenesis of Staphylococcus aureus from bovine mastitis: current understanding and future perspectives

B Campos, AC Pickering, LS Rocha, AP Aguilar… - BMC Veterinary …, 2022 - Springer
Staphylococcus aureus is a leading cause of bovine mastitis worldwide. Despite some
improved understanding of disease pathogenesis, progress towards new methods for the …

Staphylococcus aureus Secreted Toxins and Extracellular Enzymes

K Tam, VJ Torres - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a formidable pathogen capable of causing infections in different
sites of the body in a variety of vertebrate animals, including humans and livestock. A major …

[HTML][HTML] Emergence of methicillin resistance predates the clinical use of antibiotics

J Larsen, CL Raisen, X Ba, NJ Sadgrove… - Nature, 2022 - nature.com
The discovery of antibiotics more than 80 years ago has led to considerable improvements
in human and animal health. Although antibiotic resistance in environmental bacteria is …

[HTML][HTML] Bacteriophages benefit from mobilizing pathogenicity islands encoding immune systems against competitors

A Fillol-Salom, JT Rostøl, AD Ojiogu, J Chen, G Douce… - Cell, 2022 - cell.com
Bacteria encode sophisticated anti-phage systems that are diverse and versatile and display
high genetic mobility. How this variability and mobility occurs remains largely unknown …

Phage-mediated horizontal gene transfer and its implications for the human gut microbiome

T Borodovich, AN Shkoporov, RP Ross… - Gastroenterology …, 2022 - academic.oup.com
Horizontal gene transfer (HGT) in the microbiome has profound consequences for human
health and disease. The spread of antibiotic resistance genes, virulence, and pathogenicity …

Staphylococcus aureus in Animals

AF Haag, JR Fitzgerald, JR Penadés - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a mammalian commensal and opportunistic pathogen that
colonizes niches such as skin, nares and diverse mucosal membranes of about 20-30% of …

Population genomics of bacterial host adaptation

SK Sheppard, DS Guttman, JR Fitzgerald - Nature Reviews Genetics, 2018 - nature.com
Some bacteria can transfer to new host species, and this poses a risk to human health.
Indeed, an estimated 60% of all human pathogens have originated from other animal …

Bacteriophage-mediated spread of bacterial virulence genes

JR Penadés, J Chen, N Quiles-Puchalt… - Current opinion in …, 2015 - Elsevier
Highlights•Phage-mediated transduction drives bacterial evolution.•pac-phages can
package any bacterial DNA.•Both pac and cos phages can transfer mobile genetic …

[HTML][HTML] MRSA compendium of epidemiology, transmission, pathophysiology, treatment, and prevention within one health framework

M Shoaib, AI Aqib, I Muzammil, N Majeed… - Frontiers in …, 2023 - frontiersin.org
Staphylococcus aureus is recognized as commensal as well as opportunistic pathogen of
humans and animals. Methicillin resistant strain of S. aureus (MRSA) has emerged as a …

Mechanisms of Immune Evasion and Bone Tissue Colonization That Make Staphylococcus aureus the Primary Pathogen in Osteomyelitis

G Muthukrishnan, EA Masters, JL Daiss… - Current osteoporosis …, 2019 - Springer
Abstract Purpose of Review Staphylococcus aureus is the primary pathogen responsible for
osteomyelitis, which remains a major healthcare burden. To understand its dominance, here …