Autoantibodies represent a hallmark of rheumatoid arthritis (RA), with the rheumatoid factor
(RF) and antibodies against citrullinated proteins (ACPA) being the most acknowledged …

Dysregulated autoantibodies and cytokines were deemed to provide important cues for
potential illnesses, such as various carcinomas and autoimmune diseases. Increasing …

Background Identification of target antigens PLA2R, THSD7A, NELL1, or Semaphorin-3B
can explain the majority of cases of primary membranous nephropathy (MN). However …

Citrullination, the conversion of peptidyl-arginine into peptidyl-citrulline, is involved in the
breakage of self-tolerance in anti-CCP-positive rheumatoid arthritis. This reaction is …

Objective We undertook this study to estimate changes in cell‐specific DNA methylation
(DNAm) associated with methotrexate (MTX) response using whole blood samples collected …

The majority of autoimmune diseases affect more women than men, suggesting an important
role for sex hormones in regulating immune response. Current research supports this idea …

Patients with rheumatoid arthritis (RA) can test either positive or negative for circulating anti-
citrullinated protein antibodies (ACPA) and are thereby categorized as ACPA-positive …

Background Rheumatoid arthritis (RA) is an autoimmune disease with various subtypes.
Among these, seronegative rheumatoid arthritis (SnRA), distinguished by its distinctive …

Collagen type II (COL2), the main structural protein of hyaline cartilage, is considerably
affected by autoimmune responses associated with the pathogenesis of rheumatoid arthritis …

Cancer is the second leading cause of death worldwide. Today, the critical role of the
immune system in tumor control is undisputed. Checkpoint antibody immunotherapy …