Molecular mechanisms of high-altitude acclimatization

RT Mallet, J Burtscher, V Pialoux, Q Pasha… - International journal of …, 2023 - mdpi.com
High-altitude illnesses (HAIs) result from acute exposure to high altitude/hypoxia. Numerous
molecular mechanisms affect appropriate acclimatization to hypobaric and/or normobaric …

Vacuum assisted closure (VAC)/negative pressure wound therapy (NPWT) for difficult wounds: A review

P Agarwal, R Kukrele, D Sharma - Journal of clinical orthopaedics and …, 2019 - Elsevier
Delayed wound healing particularly in difficult wounds and in elderly with co morbidities is a
major concern. It leads to the pain, morbidity, prolonged treatment, and require major …

[PDF][PDF] Cardiovascular adaptations to exercise training

Y Hellsten, M Nyberg - Comprehensive physiology, 2011 - researchgate.net
Aerobic exercise training leads to cardiovascular changes that markedly increase aerobic
power and lead to improved endurance performance. The functionally most important …

Hypoxia-induced signaling in the cardiovascular system: pathogenesis and therapeutic targets

Y Zhao, W Xiong, C Li, R Zhao, H Lu, S Song… - … and Targeted Therapy, 2023 - nature.com
Hypoxia, characterized by reduced oxygen concentration, is a significant stressor that affects
the survival of aerobic species and plays a prominent role in cardiovascular diseases. From …

Exercise-induced skeletal muscle angiogenesis: impact of age, sex, angiocrines and cellular mediators

M Ross, CK Kargl, R Ferguson, TP Gavin… - European Journal of …, 2023 - Springer
Exercise-induced skeletal muscle angiogenesis is a well-known physiological adaptation
that occurs in humans in response to exercise training and can lead to endurance …

Anti-angiogenic properties of ginsenoside Rg3

M Nakhjavani, E Smith, AR Townsend, TJ Price… - Molecules, 2020 - mdpi.com
Ginsenoside Rg3 (Rg3) is a member of the ginsenoside family of chemicals extracted from
Panax ginseng. Like other ginsenosides, Rg3 has two epimers: 20 (S)-ginsenoside Rg3 …

Population history and genomic signatures for high-altitude adaptation in Tibetan pigs

H Ai, B Yang, J Li, X Xie, H Chen, J Ren - BMC genomics, 2014 - Springer
Abstract Background The Tibetan pig is one of domestic animals indigenous to the Qinghai-
Tibet Plateau. Several geographically isolated pig populations are distributed throughout the …

Negative-pressure wound therapy I: the paradox of negative-pressure wound therapy

N Kairinos, M Solomons, DA Hudson - Wound Healing Southern …, 2017 - journals.co.za
Background: Does negative-pressure wound therapy reduce or increase the pressure of
wound tissues? This seemingly obvious question has never been addressed by a study on …

Hypoxia conditioning for high-altitude pre-acclimatization

M Burtscher, GP Millet, J Burtscher - Journal of Science in Sport and …, 2022 - Springer
Purpose Main purposes of pre-acclimatization by hypoxia conditioning (HC) are the
prevention of high-altitude illnesses and maintenance of aerobic exercise performance …

White paper: an integrated perspective on the causes of hypometric metabolic scaling in animals

JF Harrison, A Biewener, JR Bernhardt… - Integrative and …, 2022 - academic.oup.com
Larger animals studied during ontogeny, across populations, or across species, usually
have lower mass-specific metabolic rates than smaller animals (hypometric scaling). This …