Human lysyl-tRNA synthetase phosphorylation promotes HIV-1 proviral DNA transcription
Y Tang, RT Behrens, C St Gelais, S Wu… - Nucleic acids …, 2023 - academic.oup.com
Human lysyl-tRNA synthetase (LysRS) was previously shown to be re-localized from its
normal cytoplasmic location in a multi-aminoacyl-tRNA synthetase complex (MSC) to the …
normal cytoplasmic location in a multi-aminoacyl-tRNA synthetase complex (MSC) to the …
QM/MM investigation of the discriminatory pre-transfer editing mechanism operated by Lysyl-tRNA synthetase
BF Ion, MM Aboelnga, JW Gauld - Journal of Biomolecular …, 2024 - Taylor & Francis
Aminoacyl-tRNA synthetases (aaRSs) are essential enzymes that remarkable facilitate the
aminoacylation process during translation. With a high fidelity, the mischarged tRNA is …
aminoacylation process during translation. With a high fidelity, the mischarged tRNA is …
Structural basis for aminoacylation of cellular modified tRNALys3 by human lysyl-tRNA synthetase
SC Devarkar, CR Budding, C Pathirage, A Kavoor… - bioRxiv, 2024 - biorxiv.org
The average eukaryotic tRNA contains 13 posttranscriptional modifications; however, their
functional impact is largely unknown. Our understanding of the complex tRNA …
functional impact is largely unknown. Our understanding of the complex tRNA …