With the rising prevalence of kidney disease, clinicians are increasingly faced with concerns
about potential thrombotic and bleeding complications. Thrombotic risk, both arterial and …

Purpose Although therapeutic dosages of most low-molecular-weight heparins (LMWHs) are
known to accumulate in patients with renal insufficiency, for the lower prophylactic dosages …

Aims Limited data are available on the impact of renal function on the outcome of patients
with atrial fibrillation (AF). Methods and results AMADEUS was a multicentre, randomized …

BACKGROUND: An increased frequency of venous thromboembolism (VTE) has been
shown in patients with decreased kidney function measured by decreased estimated …

Purpose The elimination half-life and consequently the accumulation of enoxaparin increase
as glomerular filtration rate (GFR) decreases. A dose adjustment for patients with a GFR< 30 …

Direct oral anticoagulants (DOACs) have proven efficacy and safety and are approved for
use in the prevention and treatment of thromboembolic events in patients with venous …

Background: It is well-known that patients with chronic kidney disease and end-stage renal
disease are at increased risk of pulmonary embolism than patients with normal kidney …

Background Venous thromboembolism (VTE) and renal insufficiency are common in cancer
patients. Prompt treatment is necessary to reduce the high rates of VTE-related mortality and …

Purpose The use of anticoagulants for the prevention of venous thromboembolism (VTE) in
hospitalized medical and surgical oncology patients is discussed. Summary Hospitalized …

Anticoagulant drugs, like vitamin K antagonists and heparin, have been the mainstay for the
treatment and prevention of venous thromboembolic disease for many years. Although …