Non-coding RNAs and their integrated networks
Eukaryotic genomes are pervasively transcribed. Besides protein-coding RNAs, there are
different types of non-coding RNAs that modulate complex molecular and cellular …
different types of non-coding RNAs that modulate complex molecular and cellular …
Anticancer therapy with HDAC inhibitors: mechanism-based combination strategies and future perspectives
R Jenke, N Reßing, FK Hansen, A Aigner, T Büch - Cancers, 2021 - mdpi.com
Simple Summary Beyond mutations, epigenetic changes have been described as drivers for
cancer as well. While leaving the overall DNA structure intact, they can be responsible for …
cancer as well. While leaving the overall DNA structure intact, they can be responsible for …
A step-by-step microRNA guide to cancer development and metastasis
GS Markopoulos, E Roupakia, M Tokamani… - Cellular Oncology, 2017 - Springer
Background Cancer is one of the leading causes of mortality. The neoplastic transformation
of normal cells to cancer cells is caused by a progressive accumulation of genetic and …
of normal cells to cancer cells is caused by a progressive accumulation of genetic and …
Recent trends in microRNA research into breast cancer with particular focus on the associations between microRNAs and intrinsic subtypes
S Kurozumi, Y Yamaguchi, M Kurosumi… - Journal of human …, 2017 - nature.com
MicroRNAs (miRNAs) are short non-coding RNAs that regulate the function of target genes
at the post-transcriptional phase. miRNAs are considered to have roles in the development …
at the post-transcriptional phase. miRNAs are considered to have roles in the development …
MicroRNA-125 in immunity and cancer
JK Wang, Z Wang, G Li - Cancer letters, 2019 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that play a wide variety of critical roles in
different biological processes by post-transcriptionally regulating gene expression. They …
different biological processes by post-transcriptionally regulating gene expression. They …
MicroRNAs in breast cancer: oncogene and tumor suppressors with clinical potential
W Wang, Y Luo - Journal of Zhejiang University-SCIENCE B, 2015 - Springer
MicroRNAs (miRs) are small single-stranded RNA molecules, which function as key
negative regulators of post-transcriptional modulation in almost all biological processes …
negative regulators of post-transcriptional modulation in almost all biological processes …
Targeting of erbB3 receptor to overcome resistance in cancer treatment
The erbB receptors, including the epidermal growth factor receptor (EGFR), erbB2 (also
known as HER2/neu), erbB3 (or HER3), and erbB4 (or HER4), are often aberrantly activated …
known as HER2/neu), erbB3 (or HER3), and erbB4 (or HER4), are often aberrantly activated …
Essential functions of miR‐125b in cancer
MicroRNAs (miRNAs) are small and highly conserved non‐coding RNAs that silence target
mRNAs, and compelling evidence suggests that they play an essential role in the …
mRNAs, and compelling evidence suggests that they play an essential role in the …
MicroRNAs as biomarker for breast cancer
Regardless of advances in detection and treatment, breast cancer affects about 1.5 million
women all over the world. Since the last decade, genome-wide association studies (GWAS) …
women all over the world. Since the last decade, genome-wide association studies (GWAS) …
Downregulation of the long noncoding RNA GAS5-AS1 contributes to tumor metastasis in non-small cell lung cancer
Long noncoding RNA (lncRNA) plays pivotal roles in cancer development. To date, only a
small number of lncRNAs have been characterized at functional level. Here, we discovered …
small number of lncRNAs have been characterized at functional level. Here, we discovered …