Helicobacter pylori Virulence Factors—Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment

J Baj, A Forma, M Sitarz, P Portincasa, G Garruti… - Cells, 2020 - mdpi.com
Gastric cancer constitutes one of the most prevalent malignancies in both sexes; it is
currently the fourth major cause of cancer-related deaths worldwide. The pathogenesis of …

Helicobacter pylori: an up-to-date overview on the virulence and pathogenesis mechanisms

HC Sharndama, IE Mba - Brazilian Journal of Microbiology, 2022 - Springer
Helicobacter pylori is an organism associated with ulcer disease and gastric cancer. The
latter is one of the most prevalent malignancies and currently the fourth major cause of …

The global prevalence of gastric cancer in Helicobacter pylori-infected individuals: a systematic review and meta-analysis

M Shirani, R Pakzad, MH Haddadi, S Akrami… - BMC Infectious …, 2023 - Springer
Background Helicobacter pylori is a gastrointestinal pathogen that infects around half of the
world's population. H. pylori infection is the most severe known risk factor for gastric cancer …

[HTML][HTML] Type I and type II Helicobacter pylori infection status and their impact on gastrin and pepsinogen level in a gastric cancer prevalent area

L Yuan, JB Zhao, YL Zhou, YB Qi, QY Guo… - World Journal of …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Type I Helicobacter pylori (H. pylori) infection causes severe gastric
inflammation and is a predisposing factor for gastric carcinogenesis. However, its infection …

ABO, Lewis blood group systems and secretory status with H. pylori infection in yemeni dyspeptic patients: a cross-sectional study

MA Almorish, B Al-Absi, AME Elkhalifa, E Elamin… - BMC infectious …, 2023 - Springer
Abstract Background The ABO and Lewis blood group antigens are potential factors in
susceptibility to H. pylori infection. This research aimed to examine the prevalence of …

Helicobacter pylori patient isolates from South Africa and Nigeria differ in virulence factor pathogenicity profile and associated gastric disease outcome

P Palamides, T Jolaiya, A Idowu, E Loell… - Scientific Reports, 2020 - nature.com
Helicobacter pylori is a gram-negative, spiral-shaped bacterial pathogen and the causative
agent for gastritis, peptic ulcer disease and classified as a WHO class I carcinogen. While …

Genetic basis for metronidazole and clarithromycin resistance in Helicobacter pylori strains isolated from patients with gastroduodenal disorders

SJ Hashemi, AF Sheikh, H Goodarzi… - Infection and Drug …, 2019 - Taylor & Francis
Background The aim of this study was to evaluate the antimicrobial resistance and genetic
basis for metronidazole (Mtz) and clarithromycin (Cla) resistance in strains of Helicobacter …

[HTML][HTML] EPIYA motifs of Helicobacter pylori cagA genotypes and gastrointestinal diseases in the Iranian population: a systematic review and meta-analysis

M Keikha, M Karbalaei - New Microbes and New Infections, 2021 - Elsevier
Background Helicobacter pylori (H. pylori) is one of the most well-known risk factors for
gastric cancer. Recent studies have examined the relationship between virulence factors, in …

Effect of Probiotic‐Assisted Eradication of cagA+/vacA s1m1 Helicobacter pylori on Intestinal Flora

C He, F Kong, X Chai, C Zou, X Zhu… - BioMed research …, 2022 - Wiley Online Library
Objective. We attempted to evaluate the effects of probiotic‐assisted eradication of cytotoxin‐
associated gene A (cagA)+/vacuolating cytotoxin A (vacA) s1m1 Helicobacter pylori (H …

Helicobacter pylori cagE, cagG, and cagM can be a prognostic marker for intestinal and diffuse gastric cancer

E dos Santos Pereira, LM Albuquerque… - Infection, Genetics and …, 2020 - Elsevier
It is known that Helicobacter pylori is the main cause of peptic ulceration and gastric cancer.
However, there is a lack of information on whether H. pylori strains may differ in gastric …