The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …

Fibroblast growth factors (FGFs) are small polypeptide growth factors, all of whom share in
common certain structural characteristics, and most of whom bind heparin avidly. Many …

Biological Roles of Fibroblast Growth Factor-2* | Endocrine Reviews | Oxford Academic
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Cells modulate their activities in response to signals from their surrounding environment.
Single cell organisms respond mainly to nutrient cues, many of which are able to cross the …

Fibroblast growth factors (FGFs) are key regulators of several developmental processes in
which cell fate and differentiation to various tissue lineages are determined. The importance …

In recent years, vast amounts of data on the mechanisms of neural de-and regeneration
have accumulated. However, only in disproportionally few cases has this led to efficient …

Four new members of the fibroblast growth factor (FGF) family, referred to as fibroblast
growth factor homologous factors (FHFs), have been identified by a combination of random …

The development of new blood vessels is essential to embryonic growth and throughout life
for physiological repair processes such as wound healing, post-ischaemic tissue restoration …

Purpose: FGFR1 amplification occurs in approximately 15% of estrogen receptor–positive
(ER+) human breast cancers. We investigated mechanisms by which FGFR1 amplification …

Protein toxins such as ricin and Shiga toxin with intracellular targets have to be endocytosed
and translocated to the cytosol to inhibit the protein synthesis and thereby kill the cell. Ricin …