Inflammation constitutes a complex, highly conserved cascade of molecular and cellular
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …

The emergence of pathophysiological, epidemiologic, and genetic data strongly supports
the causality for lipoprotein (a)[Lp (a)] in cardiovascular disease (CVD) and calcific aortic …

Background: Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors (i) are a class
of lipid-lowering drugs suggested to hold a plethora of beneficial effects independent of their …

Atherosclerosis, one of the life-threatening cardiovascular diseases (CVDs), has been
demonstrated to be a chronic inflammatory disease, and inflammatory and immune …

The function of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9), a novel plasma
protein, has mainly been involved in cholesterol metabolism in the liver, while, more …

Pro-protein convertase subtilisin/kexin type 9 (PCSK9) is secreted mostly by hepatocytes
and to a lesser extent by the intestine, pancreas, kidney, adipose tissue, and vascular cells …

Background PCSK9 (proprotein convertase subtilisin/kexin type 9) is well recognized for its
important role in cholesterol metabolism. Elevated levels are associated with increased …

Vascular diseases constitute a significant contributor to worldwide mortality rates, placing a
substantial strain on healthcare systems and socio-economic aspects. They are closely …

Background and aims Preclinical evidence suggests that proprotein convertase subtilisin-
kexin type 9 (PCSK9) inhibitors hold anti-inflammatory properties independently of their …

Background and aims The objective of this study was to investigate the effects of
semaglutide, a long acting glucagon-like peptide-1 receptor agonist, on atherosclerotic …