Metabolism of dendritic cells in tumor microenvironment: for immunotherapy

X Peng, Y He, J Huang, Y Tao, S Liu - Frontiers in immunology, 2021 - frontiersin.org
Dendritic cells (DCs) are a type of an antigen-presenting cell which undertake a job on
capturing antigens coming from pathogens or tumors and presenting to T cells for immune …

Dendritic-cell-vaccine-based immunotherapy for hepatocellular carcinoma: clinical trials and recent preclinical studies

LB Jeng, LY Liao, FY Shih, CF Teng - Cancers, 2022 - mdpi.com
Simple Summary This review summarizes the evidence from clinical trials and recent
preclinical studies regarding the evaluation and optimization of dendritic cells (DCs)-based …

Immune-related lncRNAs as predictors of survival in breast cancer: a prognostic signature

W Ma, F Zhao, X Yu, S Guan, H Suo, Z Tao… - Journal of Translational …, 2020 - Springer
Background Breast cancer is a highly heterogeneous disease, this poses challenges for
classification and management. Long non-coding RNAs play acrucial role in the breast …

Management of patients with intermediate stage hepatocellular carcinoma

D Prince, K Liu, W Xu, M Chen… - … advances in medical …, 2020 - journals.sagepub.com
Hepatocellular carcinoma (HCC) causes a significant health burden globally and its impact
is expected to increase in the coming years. Intermediate stage HCC, as defined by the …

Research progress in alpha-fetoprotein-induced immunosuppression of liver cancer

K Zhao, X Zhou, Y Xiao, Y Wang… - Mini Reviews in …, 2022 - ingentaconnect.com
Liver cancer is one of the most common malignant tumors, with limited treatment and 8.2%
mortality. Liver cancer is the fourth leading cause of cancer-related deaths, which seriously …

The clinical application of camrelizumab on advanced hepatocellular carcinoma

Z Chen, X Lu, K Koral - Expert Review of Gastroenterology & …, 2020 - Taylor & Francis
Introduction Camrelizumab (also known as SHR-1210), a humanized monoclonal antibody
against PD-1, has been shown to block the binding of PD-1 to PD-L1 and consequently …

The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma

L Gao, DD Xiong, X Yang, JD Li, RQ He, ZG Huang… - BMC cancer, 2022 - Springer
Background Acid phosphatase type 6 (ACP6) is a mitochondrial lipid phosphate
phosphatase that played a role in regulating lipid metabolism and there is still blank in the …

[HTML][HTML] Reprogramming the lipid metabolism of dendritic cells in tumor immunomodulation and immunotherapy

Z Sun, L Zhang, L Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Dendritic cells (DCs) are the most potent antigen-presenting cells in the human body. They
detect and process environmental signals and communicate with T cells to bridge innate …

Personalizing oncolytic virotherapy

F Hamdan, M Fusciello, V Cerullo - Human Gene Therapy, 2023 - liebertpub.com
The use of oncolytic viruses has become an attractive tool in the clinics for the treatment of
various tumor types. Such viruses are genetically modified to conditionally replicate in …

Camrelizumab: an investigational agent for hepatocellular carcinoma

B Xu, HC Sun - Expert Opinion on Investigational Drugs, 2022 - Taylor & Francis
Introduction Although many approaches have been used to treat hepatocellular carcinoma
(HCC), the clinical benefits were limited, particularly for advanced HCC. However, recent …