Iron is a crucial element for mammalian cells, considering its intervention in several
physiologic processes. Its homeostasis is finely regulated, and its alteration could be …

The liver is the major target organ of continued alcohol consumption at risk and resulting
alcoholic liver disease (ALD) is the most common liver disease worldwide. The underlying …

Background Cerebral ischemia-reperfusion injury (CIRI), a subsequent injury caused by
thrombolytic reperfusion post ischemic stroke (IS). Naotaifang (NTF) formula, a novel …

Bone regeneration remains a great clinical challenge. Low intensity near-infrared (NIR) light
showed strong potential to promote tissue regeneration, offering a promising strategy for …

The expression of the iron regulatory hormone hepcidin in hepatocytes is regulated by the
BMP‐SMAD pathway through the type I receptors ALK2 and ALK3, the type II receptors …

Diabetes has arisen as a noteworthy global health issue, marked by escalating incidence
and mortality rates. Insulin, crucial for preserving euglycemia, acts as a vital energy provider …

Liver sinusoidal endothelial cell–derived bone morphogenetic protein 6 (BMP6) and the
BMP6–small mothers against decapentaplegic homolog (SMAD) signaling pathway are …

Alcohol-related liver disease (ALD) has been long associated with changes of red blood
cells (RBC) such as macrocytosis with an elevated mean corpuscular volume (MCV) …

(1) Background: Current diagnosis of anemia in high altitude populations uses an
adjustment of observed hemoglobin (Hb) values. Such an approach has been challenged …

The iron hormone hepcidin is transcriptionally activated by iron or inflammation via distinct,
partially overlapping pathways. We addressed how iron affects inflammatory hepcidin levels …