Active pharmaceutical ingredient (API) chemicals: a critical review of current biotechnological approaches

V Kumar, V Bansal, A Madhavan, M Kumar… - …, 2022 - Taylor & Francis
The aim of this article was to generate a framework of bio-based economy by an effective
utilization of biomass from the perspectives of agriculture for developing potential end bio …

Sustainable production of natural phenolics for functional food applications

R Mark, X Lyu, JJL Lee, R Parra-Saldívar… - Journal of Functional …, 2019 - Elsevier
Phenolics are a class of plant-derived natural secondary metabolites with good anticancer,
anti-inflammatory, antimicrobial and antioxidant activities. In addition to being natural health …

Discontinuous cooperative imprinting idea based on MXene-nanocomposite membrane for high structurally stable recognition and separation of shikimic acid

Y Wu, R Lin, K Zhang, J Yan, F Ma, J Zhen… - Chemical Engineering …, 2023 - Elsevier
Abstract Ti 3 C 2 T x (MXene) has attracted wide research interest for application in various
fields due to its rich surface chemistry and 2D multilayer structure. However, its application …

Systems engineering of Escherichia coli for high-level shikimate production

Z Li, C Gao, C Ye, L Guo, J Liu, X Chen, W Song… - Metabolic …, 2023 - Elsevier
To further increase the production efficiency of microbial shikimate, a valuable compound
widely used in the pharmaceutical and chemical industries, ten key target genes contributing …

Teamed boronate affinity-functionalized Zn-MOF/PAN-derived molecularly imprinted hollow carbon electrospinning nanofibers for selective adsorption of shikimic acid

Y Zhu, K Wang, J Lu, Z Pan, J Rong… - … Applied Materials & …, 2022 - ACS Publications
Electrospun micro-/nanofibers with tailor-made specific binding sites are extremely popular
due to their tremendous potential in separation applications. In this work, teamed boronate …

Modular Engineering of l-Tyrosine Production in Escherichia coli

D Juminaga, EEK Baidoo… - Applied and …, 2012 - Am Soc Microbiol
Efficient biosynthesis of l-tyrosine from glucose is necessary to make biological production
economically viable. To this end, we designed and constructed a modular biosynthetic …

Benzene‐free synthesis of adipic acid

W Niu, KM Draths, JW Frost - Biotechnology progress, 2002 - Wiley Online Library
Strains of Escherichia coli were constructed and evaluated that synthesized cis, cis‐muconic
acid from d‐glucose under fed‐batch fermentor conditions. Chemical hydrogenation of the …

Towards bacterial strains overproducing l-tryptophan and other aromatics by metabolic engineering

M Ikeda - Applied microbiology and biotechnology, 2006 - Springer
The aromatic amino acids, l-tryptophan, l-phenylalanine, and l-tyrosine, can be
manufactured by bacterial fermentation. Until recently, production efficiency of classical …

Precise identification and transport of specific molecules through framework-functionalized membranes with multiple binding sites

K Zhang, Y Li, Z Diao, H Cui, F Ma, M Yan… - Journal of Membrane …, 2023 - Elsevier
Membranes with specific-recognition and superfast-filtration have significant practical
applications in water purification and chiral separation. However, membrane technique still …

Shikimic acid biosynthesis in microorganisms: Current status and future direction

Q Sheng, L Yi, B Zhong, X Wu, L Liu, B Zhang - Biotechnology Advances, 2023 - Elsevier
Shikimic acid (SA), a hydroaromatic natural product, is used as a chiral precursor for organic
synthesis of oseltamivir (Tamiflu®, an antiviral drug). The process of microbial production of …