Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …

Background Despite advancements in the surgical techniques of rotator cuff repair (RCR),
there remains a high retear rate. Biological augmentation of repairs with overlaying grafts …

Microfracture technique for treating articular cartilage defects usually has poor clinical
outcomes due to critical heterogeneity and extremely limited in quality. To improve the …

Tendon injuries range from acute‐related trauma to chronic‐related injuries are prevalent
and bring substantial pain, functional loss, and even disability to the patients. The …

Background Tissue engineering provides various strategies to fabricate an appropriate
microenvironment to support the repair and regeneration of lost or damaged tissues. In this …

The bone-tendon interface (BTI) is a graded structure consisting of bone, mineralized and
nonmineralized fibrocartilage, and tendons. Due to the complexity of the BTI structure, BTI …

The design of transplantable scaffolds for tissue regeneration requires gaining precise
control of topographical properties. Here, we propose a methodology to fabricate …

Orthopedic implants and bone regeneration are widely recognized as the most effective
treatments for bone tissue disorders. Despite this, there exists a substantial disparity …

Background: Repair of massive rotator cuff tears remains a challenging process with mixed
success. There is a growing interest in the use of patches to augment the repair construct …

Biomedical patches have been known as important biomaterial-based medical devices for
the clinical treatment of tissue and organ diseases. Inspired by the extracellular matrix-like …