Metallothioneins (MTs) are small cysteine-rich proteins that play important roles in metal
homeostasis and protection against heavy metal toxicity, DNA damage, and oxidative stress …

Metallothioneins (MT) are a family of ubiquitous proteins, whose role is still discussed in
numerous papers, but their affinity to some metal ions is undisputable. These cysteine-rich …

Purpose: We aimed to find key molecules associated with chemoresistance in ovarian
cancer using gene expression profiling as a screening tool. Experimental Design: Using two …

The mechanisms involved in the epithelial to mesenchymal transition (EMT) are integrated
in concert with master developmental and oncogenic pathways regulating in tumor growth …

Although surgical resection is the standard curative therapy for gastric cancer, these tumors
are often diagnosed at an advanced stage, when surgery is not recommended. Alternative …

Purpose: A major obstacle in chemotherapy is treatment failure due to anticancer drug
resistance. The emergence of acquired resistance results from host factors and genetic or …

Metallothioneins (MTs) are small cysteine-rich intracellular proteins with four major isoforms
identified in mammals, designated MT-1 through MT-4. The best known biological functions …

Gastric adenocarcinoma (GAC) is the most common histological type of gastric cancer, the
fifth according to the frequency and the third among the deadliest cancers. GAC high …

Gastric cancer, a highly heterogeneous disease, is the second leading cause of cancer
death and the fourth most common cancer globally, with East Asia accounting for more than …

Objective Cisplatin is a widely used gastric cancer (GC) chemotherapy; however, genetic
factors regulating GC responses to cisplatin remain obscure. Identifying genes regulating …