Distance distributions between paramagnetic centers in the range of 1.8 to 6 nm in
membrane proteins and up to 10 nm in deuterated soluble proteins can be measured by the …

Trapping membrane proteins in the confines of a crystal lattice obscures dynamic modes
essential for interconversion between multiple conformations in the functional cycle …

Long-range distance measurements based on paramagnetic relaxation enhancement (PRE)
in NMR, quantification of surface water dynamics near biomacromolecules by Overhauser …

Membrane proteins may be influenced by the environment, and they may be unstable in
detergents or fail to crystallize. As a result, approaches to characterize structures in a native …

The effect of several ionic liquids (ILs) on the solution structure of human serum albumin
(HSA) is revealed by continuous wave electron paramagnetic resonance (EPR) …

We present experimental evidence for the significant effect that water can have on the
functional structure of proteins in solution. Human (HSA) and Bovine Serum Albumin (BSA) …

Conspectus Protein structures are not static but sample different conformations over a range
of amplitudes and time scales. These fluctuations may involve relatively small changes in …

We present the measurement of Cu2+− Cu2+ and Cu2+− nitroxide distance distributions
using double electron− electron resonance (DEER) on a proline-based peptide and an …

The interest in the TonA protein, now called FhuA, has endured since the beginnings of
phage genetics and molecular biology. The functions of this energy-coupled transporter and …

Vitamin B12 (or cobalamin) is an enzymatic cofactor essential both for mammals and
bacteria. However, cobalamin can be synthesized only by few microorganisms so most …