Objectives Frailty is typically assessed in older populations. Identifying frailty in adults aged
under 60 years may also have value, if it supports the delivery of timely care. We sought to …

Background Age-related sensory loss and frailty are common conditions among older
adults, but epidemiologic research on their possible links has been inconclusive. Clarifying …

Background Frailty is conceptualized as an accumulation of deficits in multiple areas and is
strongly associated with the prognosis of heart failure (HF). However, the social domain of …

Background Frailty is a public health priority resulting in poor health outcomes and early
mortality in older adults. Early identification, management, and prevention of frailty may …

Background Frailty, a clinical syndrome commencing at midlife, is a risk for morbidity and
mortality. Little is known about the factors that contribute to the chronic inflammatory state …

Frailty is an important consequence of ageing, whereby frail patients are more likely to face
adverse outcomes, such as disability and death. Risk of frailty increases in people with poor …

Background This prospective study investigated whether integrating the Clinical Frailty
Scale (CFS) with a triage system would improve triage for older adult emergency department …

Circulating cell-free mitochondrial DNA (ccf-mtDNA) acts as a damage-associated molecular
pattern molecule and may be cargo within extracellular vesicles (EVs). ccf-mtDNA and select …

Objective To evaluate the predictive utility of the Hospital Frailty Risk Score (HFRS), a
stratification tool based on the ICD-10 (International Classification of Disease, Tenth …

Diet quality is a modifiable risk factor for frailty, but research on the association of frailty with
dietary inflammatory potential is limited. The objective was to determine associations …