Heterocycles occupy a salient place in chemistry due to their wide range of activity in the
fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, indole …

A sulfonamide is a functional group that is the basis of several sulfa drugs and thereby are
very much important scaffolds in medicinal as well as in synthetic organic chemistry …

Meridianins are marine-derived indole alkaloids, known to possess kinase inhibitory and
antimalarial activities. A series of N-aryl and heteroaryl sulfonamide derivatives of …

A small library of 36 new glycohybrids of phenylhydrazono-indolinones was synthesized
employing glycosylated 1, 2, 3-triazolyl-methyl-indoline-2, 3-diones and different …

In a quest to discover new drugs, we have synthesized a series of novel β-amino alcohol
grafted 1, 2, 3-triazoles and screened them for their in vitro antiplasmodial and in vivo …

We have developed a practical method to perform the reductive photocleavage of
sulfonamides using thioureas as organophotocatalysts. This transformation, which tolerates …

In an attempt to develop new antimalarial drugs, we have synthesized a new class of N-
alkylated 3-glycoconjugated-oxopropylidene oxindoles starting from substituted isatins and …

Malaria, a prevalent fatal disease around the world is caused by Plasmodium sp. and is
transmitted by the bite of female Anopheles mosquito. It is leading cause of death in this …

Neurodegenerative disorders are due to excessive neuronal apoptosis and the caspase-3
plays a key role in the apoptotic pathway. The caspase-3 inhibition may be a validated …

A pharmacophore model was generated and validated by using known human DNA ligase
inhibitors for the identification of a novel series of monocarbonyl curcumin–thiourea/thiazole …