The Krüppel-like factor (KLF) family of transcription factors regulates diverse biological
processes that include proliferation, differentiation, growth, development, survival, and …

Abstract PCR-based immunoglobulin (Ig)/T-cell receptor (TCR) clonality testing in suspected
lymphoproliferations has largely been standardized and has consequently become …

MicroRNAs (miRNAs) are a family of≈ 22-nt noncoding RNAs that can posttranscriptionally
regulate gene expression. Several miRNAs are specifically expressed in hematopoietic …

A relatively high number of different subsets of B‐cells are generated through the
differentiation of early B‐cell precursors into mature B‐lymphocytes in the bone marrow (BM) …

The contribution of proliferation to B lymphocyte homeostasis and antigen responses is
largely unknown. We quantified the replication history of mouse and human B lymphocyte …

Gross cytogenetic anomalies are traditionally being used as diagnostic, prognostic and
therapeutic markers in the clinical management of cancer, including childhood acute …

The ability to rearrange the germ-line DNA to generate antibody diversity is an essential
prerequisite for the production of a functional repertoire. While this is essential to prevent …

We examined the leukemic stem cell potential of blasts at different stages of maturation in
childhood acute lymphoblastic leukemia (ALL). Human leukemic bone marrow was …

The diagnosis of malignant lymphoma is a recognized difficult area in histopathology.
Therefore, detection of clonality in a suspected lymphoproliferation is a valuable diagnostic …

Krüppel-like factors (KLFs) are a family of zinc-finger transcription factors that are found in
many species. Recent studies have shown that KLFs play a fundamental role in regulating …