It has been 30 years since a'new'leukaemia termed adult T-cell leukaemia (ATL) was
described in Japan, and more than 25 years since the isolation of the retrovirus, human T …

The human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus discovered to be
causative of a human cancer, adult T-cell leukemia. The transforming entity of HTLV-1 has …

The HTLV Tax protein is crucial for viral replication and for initiating malignant
transformation leading to the development of adult T-cell leukemia. Tax has been shown to …

Human T-lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia
and HTLV-1-associated myelopathy/tropical spastic paraparesis. The HTLV-1 transactivator …

Hodgkin lymphoma (HL) is composed of two distinct pathological entities, nodular
lymphocyte predominant HL and classic HL, the latter with four subtypes. In contrast with …

Human T-cell lymphotropic virus type 1 (HTLV-1) has been identified as the causative agent
of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic …

Human T-cell lymphotropic virus type I (HTLV-I) is the etiologic agent of adult T-cell leukemia
(ATL), a rapidly progressing, clonal malignancy of CD4+ T lymphocytes. Fewer than one in …

HTLV-1 is the etiological agent of adult T-cell leukemia (ATL), the neurological syndrome
TSP/HAM and certain other clinical disorders. The viral Tax protein is considered to play a …

Human T-cell leukemia virus type I (HTLV-I) 1 causes adult T-cell leukemia (ATL)(1–3). The
virus is also associated with a neuropathy/myelopathy termed HTLV-associated myelopathy …

The Tax oncoprotein of human T-cell leukemia virus type 1 (HTLV-1) induces leukemia in
transgenic mice and permanent T-cell growth in vitro. In transformed lymphocytes, it acts as …