Integrative analysis of miRNA and mRNA sequencing data reveals potential regulatory mechanisms of ACE2 and TMPRSS2

S Nersisyan, M Shkurnikov, A Turchinovich… - PLoS …, 2020 - journals.plos.org
Development of novel approaches for regulating the expression of angiotensin-converting
enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) is becoming …

Interaction between endogenous microRNAs and virus-derived small RNAs controls viral replication in insect vectors

W Zhao, Q Li, M Sun, Y Xiao, F Cui - PLoS Pathogens, 2022 - journals.plos.org
MicroRNAs (miRNAs) play an important role in resisting virus infection in insects. Viruses
are recognized by insect RNA interference systems, which generate virus-derived small …

Toward a Categorization of Virus-ncRNA Interactions in the World of RNA to Disentangle the Tiny Secrets of Dengue Virus

CI Bermudez-Santana, JC Gallego-Gómez - Viruses, 2024 - mdpi.com
In recent years, the function of noncoding RNAs (ncRNAs) as regulatory molecules of cell
physiology has begun to be better understood. Advances in viral molecular biology have …

Polyubiquitylated rice stripe virus NS3 translocates to the nucleus to promote cytosolic virus replication via miRNA-induced fibrillin 2 upregulation

L Zhang, Y Li, JH Kuhn, K Zhang, Q Song, F Liu - Plos Pathogens, 2024 - journals.plos.org
Viruses are encapsidated mobile genetic elements that rely on host cells for replication.
Several cytoplasmic RNA viruses synthesize proteins and/or RNAs that translocate to …

Profound downregulation of neural transcription factor Npas4 and Nr4a family in fetal mice neurons infected with Zika virus

SP Alpuche-Lazcano, J Saliba, VV Costa… - PLoS Neglected …, 2021 - journals.plos.org
Zika virus (ZIKV) infection of neurons leads to neurological complications and congenital
malformations of the brain of neonates. To date, ZIKV mechanism of infection and …

Plant MicroRNA Potential in Targeting Sars-CoV-2 Genome Offering Efficient Antiviral MiRNA-Based Therapies

B Hajieghrari, S Rahmanian-Koshkaki - MicroRNA, 2022 - ingentaconnect.com
Background: In 2019, severe acute respiratory coronavirus II (or SARS-COV-2) emerged in
Wuhan, China, rapidly becoming a global pandemic. Coronavirus genus (Coronaviridae) …

[HTML][HTML] Prediction of binding miRNAs involved with immune genes to the SARS-CoV-2 by using sequence features extraction and One-class SVM

J Gutiérrez-Cárdenas, Z Wang - Informatics in Medicine Unlocked, 2022 - Elsevier
The prediction of host human miRNA binding to the SARS-COV-2-CoV-2 RNA sequence is
of particular interest. This biological process could lead to virus repression, serve as …