Mechanobiology is a domain of interdisciplinary research that aims to explore the impact of
physical force, applied externally or internally, on cell and tissue function, including …

Understanding the extent of inflammation is crucial for early disease detection, monitoring
disease progression, and evaluating treatment responses. Over the past decade …

Background Liver sinusoidal endothelial cells (LSECs) have transcellular pores, called
fenestrations, participating in the bidirectional transport between the vascular system and …

Portal hypertension (PH) has traditionally been observed as a consequence of significant
fibrosis and cirrhosis in advanced non-alcoholic fatty liver disease (NAFLD). However …

This thematic review aims to provide an overview of the current state of knowledge about the
occurrence of giant mitochondria or megamitochondria in liver parenchymal cells. Their …

Portal hypertension in cirrhosis is defined as an increase in the portal pressure gradient
(PPG) between the portal and hepatic veins and is traditionally estimated by the hepatic …

The metabolic syndrome, often accompanied by hepatic manifestations, is a high-risk factor
for developing cardiovascular disease. Patients with metabolic dysfunction associated with …

Mechanobiology is a rapidly emerging field focused on the biological impact of physical
forces at the molecular, cellular, and tissue level. Living cells perceive mechanical cues and …

Obesity leads to a variety of health risks, and lead, which is ranked second in Agency for
Toxic Substances and Disease Registry's priority list of harmful substances, may be more …

Background High-fat diets are associated with metabolic syndrome, cardiovascular
diseases, and liver disorders. Beef and mutton, both widely consumed meats, are significant …