Biological applications of functionalized calixarenes

SB Nimse, T Kim - Chemical Society Reviews, 2013 - pubs.rsc.org
The functionalized calixarene derivatives exhibit remarkable properties towards organic and
bioorganic molecules. However, the ability of calixarene derivatives to form stable …

Carbohydrate recognition by boronolectins, small molecules, and lectins

S Jin, Y Cheng, S Reid, M Li… - Medicinal research …, 2010 - Wiley Online Library
Carbohydrates are known to mediate a large number of biological and pathological events.
Small and macromolecules capable of carbohydrate recognition have great potentials as …

Testicular cancer biomarkers: a role for precision medicine in testicular cancer

R Leão, AE Ahmad, RJ Hamilton - Clinical genitourinary cancer, 2019 - Elsevier
Testicular germ cell tumors (TGCTs) represent the most common solid tumors among men
aged 15 to 34 years. Fortunately, recent advances have made testicular cancer a highly …

A toolbox of lectins for translating the sugar code: the galectin network in phylogenesis and tumors

H Kaltner, HJ Gabius - 2012 - digitum.um.es
Lectin histochemistry has revealed cell-type-selective glycosylation. It is under dynamic and
spatially controlled regulation. Since their chemical properties allow carbohydrates to reach …

Calix[n]arene‐Based Glycoclusters: Bioactivity of Thiourea‐Linked Galactose/Lactose Moieties as Inhibitors of Binding of Medically Relevant Lectins to a Glycoprotein …

S André, F Sansone, H Kaltner, A Casnati… - …, 2008 - Wiley Online Library
Growing insights into the functionality of lectin–carbohydrate interactions are identifying
attractive new targets for drug design. As glycan recognition is regulated by the structure of …

Cell surface glycans: the why and how of their functionality as biochemical signals in lectin-mediated information transfer

HJ Gabius - Critical Reviews™ in Immunology, 2006 - dl.begellhouse.com
Calculations of the coding capacity of biomolecules come up with the striking result that
carbohydrates excel nucleotides and amino acids by far in this respect. Consequently …

Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins: their reactivities in solid-phase and cell assays and …

S André, Z Pei, HC Siebert, O Ramström… - Bioorganic & medicinal …, 2006 - Elsevier
Dynamic combinatorial library design exploiting the thiol–disulfide exchange readily affords
access to glycosyldisulfides. In order to reveal lectin-binding properties of this type of non …

A guide to signaling pathways connecting protein-glycan interaction with the emerging versatile effector functionality of mammalian lectins

A Villalobo, A Nogales-González… - Trends in Glycoscience …, 2006 - jstage.jst.go.jp
抄録 細胞膜は細胞と外部環境との間のコミュニケーションのためのインターフェイスとしてゆるぎ
ない役割をもつ. したがって外部シグナルに対する細胞の反応性や応答能力は, 細胞表面の決定基 …

Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer

T Szöke, K Kayser, JD Baumhäkel, I Trojan, J Furak… - Oncology, 2005 - karger.com
Objective: To determine the expression of endogenous adhesion/growth-regulatory lectins
and their binding sites using labeled tissue lectins as well as the binding profile of …

Context-dependent multifunctionality of galectin-1: a challenge for defining the lectin as therapeutic target

K Smetana Jr, S André, H Kaltner, J Kopitz… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: One route of translating the information encoded in the glycan chains of cellular
glycoconjugates into physiological effects is via receptor (lectin) binding. A family of …