Fusarium: a treasure trove of bioactive secondary metabolites

M Li, R Yu, X Bai, H Wang, H Zhang - Natural product reports, 2020 - pubs.rsc.org
Covering up to December 2019 Fusarium, one of the most common fungal genera, has
received considerable attention because of its biosynthetic exuberance, the result of many …

Biosynthesis of depsipeptides, or Depsi: The peptides with varied generations

DA Alonzo, TM Schmeing - Protein Science, 2020 - Wiley Online Library
Depsipeptides are compounds that contain both ester bonds and amide bonds. Important
natural product depsipeptides include the piscicide antimycin, the K+ ionophores cereulide …

Bioinformatic Analysis of Secondary Metabolite Biosynthetic Potential in Pathogenic Fusarium

C Lin, X Feng, Y Liu, Z Li, XZ Li, J Qi - Journal of Fungi, 2023 - mdpi.com
Fusarium species are among the filamentous fungi with the most pronounced impact on
agricultural production and human health. The mycotoxins produced by pathogenic …

The transcription factor FgCrz1A is essential for fungal development, virulence, deoxynivalenol biosynthesis and stress responses in Fusarium graminearum

L Chen, Q Tong, C Zhang, K Ding - Current genetics, 2019 - Springer
The zinc finger transcription factor Crz1 is an important downstream regulator of calcium-
dependent signal transduction pathways in many organisms. The function of Crz1 in the …

Sponge-associated fungi from a mangrove habitat in Indonesia: species composition, antimicrobial activity, enzyme screening and bioactive profiling

MT Sibero, Y Igarashi, OK Radjasa, A Sabdono… - International Aquatic …, 2019 - Springer
There is no report of diversity, biological properties and bioactive compounds of sponge-
associated fungi from Indonesia's mangrove ecosystem to date. This study was designed to …

Genome Features and AntiSMASH Analysis of an Endophytic Strain Fusarium sp. R1

Y Liu, M Xu, Y Tang, Y Shao, H Wang, H Zhang - Metabolites, 2022 - mdpi.com
Endophytic fungi are one of the most prolific sources of functional biomolecules with
therapeutic potential. Besides playing an important role in serious plant diseases, Fusarium …

Enzymatic ester bond formation strategies in fungal macrolide skeletons

JM Zhang, GY Yuan, Y Zou - Natural Product Reports, 2025 - pubs.rsc.org
Covering: up to August 2024Macrolides, the core skeletons of numerous marketed drugs
and bioactive natural products, have garnered considerable scientific interest owing to their …

Bacterial-like nonribosomal peptide synthetases produce cyclopeptides in the zygomycetous fungus Mortierella alpina

JM Wurlitzer, A Stanišić, I Wasmuth… - Applied and …, 2021 - Am Soc Microbiol
Fungi are traditionally considered a reservoir of biologically active natural products.
However, an active secondary metabolism has long not been attributed to early-diverging …

Heterologous expression of intact biosynthetic gene clusters in Fusarium graminearum

MR Nielsen, RD Wollenberg, KR Westphal… - Fungal Genetics and …, 2019 - Elsevier
Filamentous fungi such as species from the genus Fusarium are capable of producing a
wide palette of interesting metabolites relevant to health, agriculture and biotechnology …

Advances in linking polyketides and non-ribosomal peptides to their biosynthetic gene clusters in Fusarium

MR Nielsen, TE Sondergaard, H Giese, JL Sørensen - Current Genetics, 2019 - Springer
The eukaryotic ascomycete genus Fusarium comprises many species capable of producing
secondary metabolites important for agriculture, health, and biotechnology. Filamentous …