Cocrystals; basic concepts, properties and formation strategies

S Khan, M Zahoor, MU Rahman, Z Gul - Zeitschrift für Physikalische …, 2023 - degruyter.com
Cocrystallization is an old technique and remains the focus of several research groups
working in the field of Chemistry and Pharmacy. This technique is basically in field for …

Formulation of eutectic mixture of curcumin with salicylic acid for improving its dissolution profile

S Narwal, A Kumar, M Chaudhary… - Research Journal of …, 2021 - indianjournals.com
Background: Eutectics are basically multi-component crystalline solids closely related to
solid solutions. However, the structural organization of eutectics has not been studied in as …

Green approach towards Synthesis and structural analysis of benzocaine-based compound and its co-crystals

J Dontulwar, AG Kondalkar - 2023 - indianjournals.com
The pharmaceutical cocrystals have sparked a lot of attention because of their ability to
improve a drug's physicochemical flaws, like poor water solubility. The amino carboxylic …

The Effect of pH and Cocrystal Quercetin-Isonicotinamide on Quercetin Solubility and its Thermodynamic

B Wisudyaningsih, S Sallama… - Research Journal of …, 2021 - indianjournals.com
This study aimed to improve the solubility of quercetin by solvent pH control method and
crystal modification through co-crystal formation using isonicotinamide as its co-former …

Enhancement of physicochemical and pharmacokinetic characteristics of ranolazine drug substance using cocrystalization technique

G Vyas, J Shah, S Jacob - Research Journal of Pharmacy and …, 2024 - indianjournals.com
Biopharmaceutical Classification System II drug, Ranolazine exhibits pH-dependent
solubility and thus shows variable absorption along the gastrointestinal tract. Due to poor …

Evaluation of the Antilithiasic activity, Phospho-ammoniaco-magnésien of the aqueous extract of Fraxinus excelsior (L.)

K Ghenaiet, A Boutefnouchet, A Lekouaghet… - 2022 - indianjournals.com
The formation of urinary stones is a serious clinical problem in the world, the struvite of
which is one of the characteristic components of urolithiasis of infectious origin. The …

Developing New Treatment Modalities From Poorly Dissolvable Antihypertensive: Courtesy Delivery System Design &Niche Technologies

PK Sharma, VK Shukla, A Kumar, R Sharma - International journal of health … - neliti.com
Most antihypertensive drugs have impaired dissolution rate and result from poorly aqueous
solubility, polymorphic modifications, structure-based H-bond donor or acceptor anamolies …

[PDF][PDF] PHARMACEUTICAL SCIENCES

PMMNL Varma, M Hemalatha, MJ Sai, BD Lakshmi… - academia.edu
Poor aqueous solubility and low oral bioavailability of an active pharmaceutical ingredient
are the limitations during the growth of a new product. Co-crystal formation is a new …

Formulation and Solid-State Characterisation of a Novel Benzanilide Co-crystal of the Anti-HIV Drug Efavirenz

MA Jordaan, M Shapi - Journal of Pharmacy and Pharmacology, 2018 - papers.ssrn.com
HIV/AIDS has had a crippling socio-economic effect on developing countries in Africa. EFV
(Efavirenz) is generally used to treat this pathology. However, its clinical efficacy is reduced …