RNAi efficiency, systemic properties, and novel delivery methods for pest insect control: what we know so far

MR Joga, MJ Zotti, G Smagghe… - Frontiers in physiology, 2016 - frontiersin.org
In recent years, the research on the potential of using RNA interference (RNAi) to suppress
crop pests has made an outstanding growth. However, given the variability of RNAi …

Model systems for the study of Enterococcal colonization and infection

HMS Goh, MHA Yong, KKL Chong, KA Kline - Virulence, 2017 - Taylor & Francis
Enterococcus faecalis and Enterococcus faecium are common inhabitants of the human
gastrointestinal tract, as well as frequent opportunistic pathogens. Enterococci cause a …

Molecular toxicology in Caenorhabditis elegans

D Wang - Nematodes as Model Organisms, 2022 - cabidigitallibrary.org
This chapter focuses on the introduction of molecular signaling pathways involved in
regulating the toxicity of environmental toxicants or stresses in Caenorhabditis elegans …

Application of Caenorhabditis elegans in Lipid Metabolism Research

L An, X Fu, J Chen, J Ma - International journal of molecular sciences, 2023 - mdpi.com
Over the last decade, the development and prevalence of obesity have posed a serious
public health risk, which has prompted studies on the regulation of adiposity. With the ease …

NHR-49/PPAR-α and HLH-30/TFEB cooperate for C. elegans host defense via a flavin-containing monooxygenase

KA Wani, D Goswamy, S Taubert, R Ratnappan… - Elife, 2021 - elifesciences.org
The model organism Caenorhabditis elegans mounts transcriptional defense responses
against intestinal bacterial infections that elicit overlapping starvation and infection …

Caenorhabditis elegans for research on cancer hallmarks

J Cerón - Disease Models & Mechanisms, 2023 - journals.biologists.com
After decades of research, our knowledge of the complexity of cancer mechanisms,
elegantly summarized as 'hallmarks of cancer', is expanding, as are the therapeutic …

NHR-49 transcription factor regulates immunometabolic response and survival of Caenorhabditis elegans during Enterococcus faecalis infection

M Dasgupta, M Shashikanth, A Gupta… - Infection and …, 2020 - Am Soc Microbiol
Immune response to pathogens is energetically expensive to the host; however, the cellular
source of energy to fuel immune response remains unknown. In this study, we show that …

The role of ErbB receptors in infection

J Ho, DL Moyes, M Tavassoli, JR Naglik - Trends in microbiology, 2017 - cell.com
Members of the epidermal growth factor receptor family (ErbB family) possess a wide
distribution and diverse functions ranging from cellular growth to migration and apoptosis …

Reciprocal interactions between nematodes and their microbial environments

A Midha, J Schlosser, S Hartmann - Frontiers in Cellular and Infection …, 2017 - frontiersin.org
Parasitic nematode infections are widespread in nature, affecting humans as well as wild,
companion, and livestock animals. Most parasitic nematodes inhabit the intestines of their …

Nuclear hormone receptor NHR-49 is an essential regulator of stress resilience and healthy aging in Caenorhabditis elegans

KRS Doering, G Ermakova, S Taubert - Frontiers in Physiology, 2023 - frontiersin.org
The genome of Caenorhabditis elegans encodes 284 nuclear hormone receptor, which
perform diverse functions in development and physiology. One of the best characterized of …