Notch signaling is involved in cell fate determination and deregulated in human solid
tumors. Hypoxia is an important feature in many solid tumors, which activates hypoxia …

The Notch signaling pathway is an evolutionarily conserved pathway that modulates normal
biological processes involved in cellular differentiation, apoptosis, and stem cell self …

Simple Summary The dysregulation of Notch signaling plays an important role in cancer
development. Numerous attempts are made to modulate Notch signaling for positive …

Background Fringe is a glycosyltransferase involved in tumor occurrence and metastasis.
However, a comprehensive analysis of the Fringe family members lunatic fringe (LFNG) …

The Notch signaling pathway plays pivotal roles in cell proliferation, stemness and invasion
of non-small cell lung cancer (NSCLC). The human Notch family consists of four receptors …

Uterine corpus endometrial carcinoma (UCEC) has a strong ability of invasion and
metastasis, high recurrence rate, and poor survival. Glycosyltransferases are one of the most …

Notch pathway is a widely observed signaling system that holds pivotal functions in
regulating various developmental cellular functions and operations. The Notch signaling …

A fundamental event in the formation of heart valves involves the transformation of
endocardial cells within the out ow tract (OFT) and atrioventricular canal (AVC) cushions …

Background Protein glycosylation plays an important role in various biological processes,
and abnormal glycosylation is often linked with many diseases. This study aimed to …