Identifying, understanding, and managing fecal urgency in inflammatory bowel diseases

B Caron, S Ghosh, S Danese… - Clinical Gastroenterology …, 2023 - Elsevier
Background & Aims Fecal urgency, which is defined by the sudden need to rush to the
bathroom to empty one's bowel, is one of the common and distressing symptoms …

Paeoniflorin alleviates inflammatory response in IBS-D mouse model via downregulation of the NLRP3 inflammasome pathway with involvement of miR-29a

W Ke, Y Wang, S Huang, S Liu, H Zhu, X Xie, H Yang… - Heliyon, 2022 - cell.com
Paeoniflorin has been traditionally used to treat pain and immunologic derangement in
China. However, its detailed mechanism remains to be illuminated. We investigated the …

[HTML][HTML] Rifaximin treatment for individual and multiple symptoms of irritable bowel syndrome with diarrhea: An analysis using new end points

BE Lacy, L Chang, SSC Rao, Z Heimanson… - Clinical …, 2023 - Elsevier
Purpose Rifaximin is indicated for the treatment of irritable bowel syndrome with diarrhea
(IBS-D) in adults. The current aim was to evaluate rifaximin efficacy on individual and …

Prevalence and clinical impact of the London classification: a prospective, international, multicenter study from the Lower Gastrointestinal International Consortium …

PF Vollebregt, PT Heitmann, H Damon… - Official journal of the …, 2022 - journals.lww.com
Methods: An international research consortium was established, including five specialist
centers. Prospective data were collected in consecutive adults referred for refractory chronic …

Rectal Evacuation Disorders in Patients Presenting With Chronic Functional Diarrhea

W Sannaa, J BouSaba, Y Magnus… - Gastro Hep …, 2022 - pmc.ncbi.nlm.nih.gov
Defecatory disorders include a spectrum of conditions that manifest as spastic rectal
evacuation disorders or flaccid disorders causing obstructed defecation. 1 Functional …