Oligopeptidase B is a “processing peptidase” from the prolyl oligopeptidase family of serine
peptidases present in Gram negative bacteria, protozoa and plants. Unlike the prototype …

Serine proteases have significant functions over a broad range of relevant biological
processes to the Leishmania spp lifecycle. Data gathered here present an update on the …

We evaluated the effectiveness of serological and parasitological methods for cutaneous
leishmaniasis (CL) diagnosis in patients from the central region of Paraná state, southern …

Trypanosoma brucei contains a soluble serine oligopeptidase (OP-Tb) that is released into
the host bloodstream during infection, where it has been postulated to participate in the …

Leishmania causes tegumental and visceral diseases called leishmaniasis. Disease control
is possible interrupting the transmission cycle, but HIV co-infection, chemotheraphy toxicity …

To investigate the importance of serine proteases in Leishmania amazonensis
promastigotes, we analyzed the effects of classical serine protease inhibitors and a Kunitz …

Serine oligopeptidases of trypanosomatids are emerging as important virulence factors and
therapeutic targets in trypanosome infections. A complete open reading frame of …

Pathogenic protozoan proteases play crucial roles in the host–parasite interaction, and its
characterization contributes to the understanding of protozoan disease mechanisms. A …

In most organisms around 2% of the genes code for peptidases being this number only
surmounted by the genes that code for transcriptional factors. This ubiquitous presence is …

Two novel intracellular proteases having identical molecular mass (58 kDa) were purified
from virulent Indian strain of Leishmania donovani by a combination of aprotinin-agarose …