Calixarenes (CAs), representing the third generation of supramolecular hosts and one of the
most widely studied macrocyclic scaffolds, offer (almost) unlimited structure and application …

Paracoccidioidomycosis is a neglected disease that causes economic and social impacts,
mainly affecting people of certain social segments, such as rural workers. The limitations of …

The use of functionalized calix-and thia-calix [n] arenes is proposed as the basis for our in
silico design of a suitable drug carrier for the tyrosine kinase inhibitor, Imatinib. Their mutual …

The suitability of eight differently substituted calix [n] arenes (with R=-OEt; SO 3 H and n= 4,
5, 6, 8) as drug delivery agents for 3-phenyl-1H-[1] benzofuro [3, 2-c] pyrazole (henceforth …

Introduction Cocaine use disorder is a significant public health issue without a current
specific approved treatment. Among different approaches to this disorder, it is possible to …

Calixarenes and functionalized calixarenes unique three dimensional structures and large
scale synthesis allows supramolecular interactions and complex-formation with a variety of …

The antibacterial activity of a calixarene derivative, p-tert-butylcalix [6] arene (Calix6), was
assessed and was shown not to inhibit the growth of E. coli, S. aureus and B. subtilis …

Calix [n] arenes are macrocyclic cone-shaped compounds formed from phenolic units linked
by methylene groups in the ortho position. Structural features make calix [n] arenes a …

Ketoconazole (KTZ) is an antifungal agent; however, its bioavailability and therapeutic
efficacy are reduced by the low aqueous solubility of the drug. Aiming at providing to …

Calixarene (CAs) stellen die dritte Generation supramolekularer Wirtsstrukturen dar und
sind eine der am häufigsten untersuchten makrocyclischen Gerüststrukturen. Sie bieten …