Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and
represents a high-grade neoplasm of skeletal myoblast-like cells. Decades of clinical and …

Advances in the treatment of childhood cancers have resulted in part from the development
of national and international collaborative initiatives that have defined biologic determinants …

Acute leukemia is the most common cancer in children but the causes of the disease in the
majority of cases are not known. About 80% are precursor-B cell in origin (CD19+, CD10+) …

Childhood cancer burden is shifted toward LMICs; global initiatives directed at pediatric
cancer care and control are urgently needed. International partnerships facilitating stepwise …

Although the cure rates of childhood acute lymphoblastic leukemia (ALL) have improved
dramatically in the past 40 years, not all children have benefited equally from this impressive …

Purpose Recent genome-wide screens have identified genetic variations in ARID5B
associated with susceptibility to childhood acute lymphoblastic leukemia (ALL). We sought …

Improvements in risk-directed treatment and supportive care, together with increased
reliance on both national and international collaborative studies, have made childhood …

Childhood leukemia is the most common cancer diagnosed in children worldwide. However,
only a few causes have been established so far, mainly some genetic syndromes and high …

Background The male excess in childhood cancer incidence is well‐established; however,
the underlying biologic mechanisms remain unknown. Examining the association between …

Childhood leukemias are heterogeneous diseases with widely differing incident rates
worldwide. As circulating tumors, childhood acute leukemias are uniquely accessible, and …