Lornoxicam controlled release transdermal gel patch: Design, characterization and optimization using co-solvents as penetration enhancers

D Hashmat, MH Shoaib, FR Ali, F Siddiqui - Plos one, 2020 - journals.plos.org
The aim of the current study was to develop membrane-based transdermal patches of
lornoxicam gel using oleic acid (OA) and propylene glycol (PG) as penetration enhancers to …

Development of triptolide-nanoemulsion gels for percutaneous administration: physicochemical, transport, pharmacokinetic and pharmacodynamic characteristics

M Yang, Y Gu, D Yang, X Tang, J Liu - Journal of Nanobiotechnology, 2017 - Springer
Background This work aimed to provide useful information on the use of nanoemulsions for
the percutaneous administration of triptolide. Lipid nanosystems have great potential for …

Development and optimization of nanoemulsion based gel for enhanced transdermal delivery of nitrendipine using box-behnken statistical design

A Sharma, AP Singh, SL Harikumar - Drug development and …, 2020 - Taylor & Francis
Objective: The purpose of present research was to develop and statistically optimize
nitrendipine nanoemulsion gel for transdermal delivery using box-behnken statistical …

Systemic delivery of antihypertensive drugs via skin

S Güngör, Y Özsoy - Therapeutic delivery, 2012 - Taylor & Francis
Hypertension is a chronic disease with one of the highest chances of causing death, and
long-term treatment is required. The antihypertensive drugs used in the treatment are …

Formulation, in vitro, and in vivo evaluation of matrix-type transdermal patches containing olanzapine

G Aggarwal, S Dhawan… - Pharmaceutical …, 2013 - Taylor & Francis
Transdermal patches of olanzapine were aimed to be prepared to overcome the side effects
by oral application. The strategy was formulation of eudragit-based polymeric films to …

Formulation development and evaluation, in silico PBPK modeling and in vivo pharmacodynamic studies of clozapine matrix type transdermal patches

A Qadir, SU Jan, MH Shoaib, M Sikandar, RI Yousuf… - Scientific Reports, 2025 - nature.com
Clozapine is a potent serotonin receptor antagonist and commonly used for the treatment of
Schizophrenia. The study aimed to develop and optimize the transdermal matrix patch of …

Natural oils as skin permeation enhancers for transdermal delivery of olanzapine: in vitro and in vivo evaluation

G Aggarwal, S Dhawan, S L. HariKumar - Current Drug Delivery, 2012 - benthamdirect.com
The feasibility of development of transdermal delivery system of olanzapine utilizing natural
oils as permeation enhancers was investigated. Penetration enhancing potential of corn …

Optimization and in vivo evaluation of quetiapine-loaded transdermal drug delivery system for the treatment of schizophrenia

MB Agrawal, MM Patel - Drug development and industrial …, 2020 - Taylor & Francis
The prevailing studies were carried out to formulate and optimize the quetiapine transdermal
matrix patch by the usage of Box–Behnken design for ameliorated bioavailability when …

Pharmacokinetic investigation of nitrendipine encapsulated niosomal gel in rat plasma by RP-HPLC method

A Sharma, R Sharma, KS Bora, SL Harikumar - Materials Today …, 2022 - Elsevier
The investigation was intended to develop niosomal gel and determination of bioavailability
of nitrendipine by pharmacokinetic method via using Albino Wistar rats. The drug …

Formulation and Evaluation of Niosomal Loaded Transdermal Patches for the Treatment of Osteoarthritis

Kajal, DR Sharma, V Pandit, M Ashawat - Drug Delivery Letters, 2024 - benthamdirect.com
Introduction Osteoarthritis (OA) is a degenerative joint disease resulting from the breakdown
of joint cartilage and underlying bone. The most common symptoms of osteoarthritis are joint …