Platinum group metal (PGM) complexes having acylthiourea ligand system as catalysts or anticancer agents

S Swaminathan, P Jerome, RJ Deepak… - Coordination Chemistry …, 2024 - Elsevier
The intention behind the design of a metal complex is quite crucial for its development
towards a particular application. Transition metal complexes have tremendously become …

Exploring the latest trends in chemistry, structure, coordination, and diverse applications of 1-acyl-3-substituted thioureas: a comprehensive review

SA Ullah, A Saeed, M Azeem, MB Haider, MF Erben - RSC advances, 2024 - pubs.rsc.org
Acyl thioureas represent a privileged moiety with vast potential applicability across diverse
fields, making them the subject of extensive research efforts. The inherent flexibility of …

Effective and selective Ru (II)-arene complexes containing 4, 4′-substituted 2, 2′ bipyridine ligands targeting human urinary bladder cancer cells

M Muralisankar, JR Chen, J Haribabu… - International Journal of …, 2023 - mdpi.com
Cisplatin-based chemotherapy is a common regimen for bladder cancer, a life-threatening
cancer with more than 500,000 new cases worldwide annually. Like many other …

Multifaceted exploration of acylthiourea compounds: In vitro cytotoxicity, DFT calculations, molecular docking and dynamics simulation studies

J Haribabu, G Madhavan, S Swaminathan… - International Journal of …, 2024 - Elsevier
This study reports the synthesis and analysis of biologically active acylthiourea compounds
(1 and 2) with a cyclohexyl moiety. The compounds were characterized using UV–Visible …

Bis (acylthiourea) compounds as enzyme inhibitors: Synthesis, characterization, crystal structures and in silico molecular docking studies

P Jerome, J Haribabu, DP Dorairaj, M Azam… - Journal of Molecular …, 2024 - Elsevier
A series of bis (acylthiourea) compounds was synthesized and characterized by various
spectroscopic and analytical methods. The structures of the three compounds were …

Insights into the antineoplastic activity and mechanisms of action of coumarin-coordinated 8-hydroxyquinoline ruthenium (II/III) compounds

LQ Du, Y Yang, L Ruan, S Sun, DY Mo, JY Cai… - Journal of Inorganic …, 2024 - Elsevier
Ruthenium (II/III) coordination compounds have gained widespread attention as
chemotherapy drugs, photosensitizers, and photodynamic therapy reagents. Herein, a family …

In vitro cytotoxic study of synthesized Ag and Ce dual-doped α-Fe2O3 nanoparticles on NIH/3T3 and U87 cell lines

M Sarani, M Barani, S Darijani, M Adeli-Sardou… - Inorganic Chemistry …, 2024 - Elsevier
The significant potential of iron oxide nanoparticles in biomedical fields, particularly in the
delivery of anticancer drugs and in sono-chemodynamic therapy, can be attributed to their …

Dinuclear arene ruthenium (II) arylthiourea complexes: Synthesis, structure, cancer cell growth inhibition and apoptosis induction studies

S Balaji, MKM Subarkhan… - Applied …, 2024 - Wiley Online Library
New half‐sandwich dinuclear arene ruthenium complexes of the general formula [(η6‐p‐
cymene) Ru (k2‐S‐arylthiourea) Cl](1–3) have been synthesized. The structural …

Fabrication of marizomib-loaded zeolitic imidazolate framework-8@ manganese dioxide for promising drug delivery system of glioma cancer cells

J Jing, Q Meng, AH Hirad, MK Ramar - Process Biochemistry, 2023 - Elsevier
Marizomib is a novel, irreversible, brain-penetrant pan-proteasome inhibitor with
encouraging findings in preclinical models and early-stage clinical trials for patients with …

Promoting the Anticancer Activity with Multidentate Furan-2-Carboxamide Functionalized Aroyl Thiourea Chelation in Binuclear Half-Sandwich Ruthenium (II) …

SK Thangavel, MS Mohamed Kasim… - Inorganic …, 2024 - ACS Publications
A new set of binuclear arene ruthenium complexes [Ru2 (p-cymene) 2 (k4-N2OS)(L1-L3)
Cl2](Ru 2 L1–Ru 2 L3) encompassing furan-2-carboxamide-based aroylthiourea derivatives …